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dc.creatorDimitrijević, Mirjana
dc.creatorStanojević, Stanislava
dc.creatorVujić, Vesna
dc.creatorAleksić, Iva
dc.creatorPilipović, Ivan
dc.creatorLeposavić, Gordana
dc.date.accessioned2019-09-02T11:38:22Z
dc.date.available2019-09-02T11:38:22Z
dc.date.issued2014
dc.identifier.issn1389-5729
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/2073
dc.description.abstractAltered functions of macrophages with aging contribute to impairment of both innate and adaptive immunity in the elderly. The present study aimed to examine strain specificity of age-related changes in the phenotypic and functional characteristics of macrophages from DA and AO rats, which differ in average life span. Resident peritoneal macrophages from young (10-12 weeks old) and aged (98-104 weeks old) rats were tested for: (a) the surface expression of TLR4 and CD14; (b) the basal and LPS-induced production of TNF-alpha and IL-10; anden
dc.publisherSpringer, New York
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/175050/RS//
dc.rightsrestrictedAccess
dc.sourceBiogerontology
dc.subjectAgingen
dc.subjectMacrophagesen
dc.subjectCytokinesen
dc.subjectNO/urea balanceen
dc.subjectDP4en
dc.subjectRat strainsen
dc.titleAging oppositely affects TNF-alpha and IL-10 production by macrophages from different rat strainsen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractДимитријевић, Мирјана; Станојевић, Станислава; Вујић, Весна; Лепосавић, Гордана; Пилиповић, Иван; Aлексић, Ива;
dc.citation.volume15
dc.citation.issue5
dc.citation.spage475
dc.citation.epage486
dc.citation.other15(5): 475-486
dc.citation.rankM22
dc.identifier.wos000342080300006
dc.identifier.doi10.1007/s10522-014-9513-4
dc.identifier.pmid25009084
dc.identifier.scopus2-s2.0-84906936202
dc.identifier.rcubconv_3158
dc.type.versionpublishedVersion


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