dc.creator | Dimitrijević, Mirjana | |
dc.creator | Stanojević, Stanislava | |
dc.creator | Vujić, Vesna | |
dc.creator | Aleksić, Iva | |
dc.creator | Pilipović, Ivan | |
dc.creator | Leposavić, Gordana | |
dc.date.accessioned | 2019-09-02T11:38:22Z | |
dc.date.available | 2019-09-02T11:38:22Z | |
dc.date.issued | 2014 | |
dc.identifier.issn | 1389-5729 | |
dc.identifier.uri | https://farfar.pharmacy.bg.ac.rs/handle/123456789/2073 | |
dc.description.abstract | Altered functions of macrophages with aging contribute to impairment of both innate and adaptive immunity in the elderly. The present study aimed to examine strain specificity of age-related changes in the phenotypic and functional characteristics of macrophages from DA and AO rats, which differ in average life span. Resident peritoneal macrophages from young (10-12 weeks old) and aged (98-104 weeks old) rats were tested for: (a) the surface expression of TLR4 and CD14; (b) the basal and LPS-induced production of TNF-alpha and IL-10; and | en |
dc.publisher | Springer, New York | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/175050/RS// | |
dc.rights | restrictedAccess | |
dc.source | Biogerontology | |
dc.subject | Aging | en |
dc.subject | Macrophages | en |
dc.subject | Cytokines | en |
dc.subject | NO/urea balance | en |
dc.subject | DP4 | en |
dc.subject | Rat strains | en |
dc.title | Aging oppositely affects TNF-alpha and IL-10 production by macrophages from different rat strains | en |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Димитријевић, Мирјана; Станојевић, Станислава; Вујић, Весна; Лепосавић, Гордана; Пилиповић, Иван; Aлексић, Ива; | |
dc.citation.volume | 15 | |
dc.citation.issue | 5 | |
dc.citation.spage | 475 | |
dc.citation.epage | 486 | |
dc.citation.other | 15(5): 475-486 | |
dc.citation.rank | M22 | |
dc.identifier.wos | 000342080300006 | |
dc.identifier.doi | 10.1007/s10522-014-9513-4 | |
dc.identifier.pmid | 25009084 | |
dc.identifier.scopus | 2-s2.0-84906936202 | |
dc.type.version | publishedVersion | |