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Contribution to interaction between magnesium and toxic metals: The effect of prolonged cadmium intoxication on magnesium metabolism in rabbits

Нема приказа
Аутори
Soldatović, Danilo
Matović, Vesna
Vujanović, Dragana
Stojanović, Z
Чланак у часопису (Објављена верзија)
Метаподаци
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Апстракт
The results obtained up to now indicate that increased intake of some heavy metals causes disorder of bioelements metabolism leading to their blood and organs decrease and higher elimination via the urine. As to lead and magnesium, our investigations indicated that the reaction is reversible and that increased intake of Mg eliminates Pb via urine. Some other findings suggest similar relations between Mg and certain heavy metals, thus pointing to significant role of Mg in toxicology of heavy metals and announcing a new chapter in the toxicology of metals entitled 'Mg in professional and ecotoxicology'. In this report we present the results of our investigations on the effect of Cd on Mg metabolism. The experiment was performed on rabbits given orally, every day, for 4 weeks 10 mg Cd/kg b.w. as aqueous solution of CdCl 2 . Magnesium content was determined in blood, urine, soft tissues and bones by the AAS method. Under the experimental conditions, Cd lead to statistically significant dec...rease of blood Mg (p < 0.001 after day 16) which was associated with increased Mg elimination via urine (p < 0.01). Statistically significant changes were not detected in the tissues, except in the liver where we found enhanced Mg content (p < 0.05), while its level in the muscles decreased (p < 0.01).

Кључне речи:
Blood / Cadmium / Magnesium / Organs / Rabbits / Urine
Извор:
Magnesium Research, 1998, 11, 4, 283-288
Издавач:
  • John Libbey Eurotext

ISSN: 0953-1424

Scopus: 2-s2.0-0032239827
[ Google Scholar ]
23
Handle
https://hdl.handle.net/21.15107/rcub_farfar_211
URI
https://farfar.pharmacy.bg.ac.rs/handle/123456789/211
Колекције
  • Radovi istraživača / Researchers’ publications
Институција/група
Pharmacy
TY  - JOUR
AU  - Soldatović, Danilo
AU  - Matović, Vesna
AU  - Vujanović, Dragana
AU  - Stojanović, Z
PY  - 1998
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/211
AB  - The results obtained up to now indicate that increased intake of some heavy metals causes disorder of bioelements metabolism leading to their blood and organs decrease and higher elimination via the urine. As to lead and magnesium, our investigations indicated that the reaction is reversible and that increased intake of Mg eliminates Pb via urine. Some other findings suggest similar relations between Mg and certain heavy metals, thus pointing to significant role of Mg in toxicology of heavy metals and announcing a new chapter in the toxicology of metals entitled 'Mg in professional and ecotoxicology'. In this report we present the results of our investigations on the effect of Cd on Mg metabolism. The experiment was performed on rabbits given orally, every day, for 4 weeks 10 mg Cd/kg b.w. as aqueous solution of CdCl 2 . Magnesium content was determined in blood, urine, soft tissues and bones by the AAS method. Under the experimental conditions, Cd lead to statistically significant decrease of blood Mg (p < 0.001 after day 16) which was associated with increased Mg elimination via urine (p < 0.01). Statistically significant changes were not detected in the tissues, except in the liver where we found enhanced Mg content (p < 0.05), while its level in the muscles decreased (p < 0.01).
PB  - John Libbey Eurotext
T2  - Magnesium Research
T1  - Contribution to interaction between magnesium and toxic metals: The effect of prolonged cadmium intoxication on magnesium metabolism in rabbits
VL  - 11
IS  - 4
SP  - 283
EP  - 288
UR  - https://hdl.handle.net/21.15107/rcub_farfar_211
ER  - 
@article{
author = "Soldatović, Danilo and Matović, Vesna and Vujanović, Dragana and Stojanović, Z",
year = "1998",
abstract = "The results obtained up to now indicate that increased intake of some heavy metals causes disorder of bioelements metabolism leading to their blood and organs decrease and higher elimination via the urine. As to lead and magnesium, our investigations indicated that the reaction is reversible and that increased intake of Mg eliminates Pb via urine. Some other findings suggest similar relations between Mg and certain heavy metals, thus pointing to significant role of Mg in toxicology of heavy metals and announcing a new chapter in the toxicology of metals entitled 'Mg in professional and ecotoxicology'. In this report we present the results of our investigations on the effect of Cd on Mg metabolism. The experiment was performed on rabbits given orally, every day, for 4 weeks 10 mg Cd/kg b.w. as aqueous solution of CdCl 2 . Magnesium content was determined in blood, urine, soft tissues and bones by the AAS method. Under the experimental conditions, Cd lead to statistically significant decrease of blood Mg (p < 0.001 after day 16) which was associated with increased Mg elimination via urine (p < 0.01). Statistically significant changes were not detected in the tissues, except in the liver where we found enhanced Mg content (p < 0.05), while its level in the muscles decreased (p < 0.01).",
publisher = "John Libbey Eurotext",
journal = "Magnesium Research",
title = "Contribution to interaction between magnesium and toxic metals: The effect of prolonged cadmium intoxication on magnesium metabolism in rabbits",
volume = "11",
number = "4",
pages = "283-288",
url = "https://hdl.handle.net/21.15107/rcub_farfar_211"
}
Soldatović, D., Matović, V., Vujanović, D.,& Stojanović, Z.. (1998). Contribution to interaction between magnesium and toxic metals: The effect of prolonged cadmium intoxication on magnesium metabolism in rabbits. in Magnesium Research
John Libbey Eurotext., 11(4), 283-288.
https://hdl.handle.net/21.15107/rcub_farfar_211
Soldatović D, Matović V, Vujanović D, Stojanović Z. Contribution to interaction between magnesium and toxic metals: The effect of prolonged cadmium intoxication on magnesium metabolism in rabbits. in Magnesium Research. 1998;11(4):283-288.
https://hdl.handle.net/21.15107/rcub_farfar_211 .
Soldatović, Danilo, Matović, Vesna, Vujanović, Dragana, Stojanović, Z, "Contribution to interaction between magnesium and toxic metals: The effect of prolonged cadmium intoxication on magnesium metabolism in rabbits" in Magnesium Research, 11, no. 4 (1998):283-288,
https://hdl.handle.net/21.15107/rcub_farfar_211 .

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