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dc.creatorSoldatović, Danilo
dc.creatorMatović, Vesna
dc.creatorVujanović, Dragana
dc.creatorStojanović, Z
dc.date.accessioned2019-09-02T10:51:16Z
dc.date.available2019-09-02T10:51:16Z
dc.date.issued1998
dc.identifier.issn0953-1424
dc.identifier.urihttps://farfar.pharmacy.bg.ac.rs/handle/123456789/211
dc.description.abstractThe results obtained up to now indicate that increased intake of some heavy metals causes disorder of bioelements metabolism leading to their blood and organs decrease and higher elimination via the urine. As to lead and magnesium, our investigations indicated that the reaction is reversible and that increased intake of Mg eliminates Pb via urine. Some other findings suggest similar relations between Mg and certain heavy metals, thus pointing to significant role of Mg in toxicology of heavy metals and announcing a new chapter in the toxicology of metals entitled 'Mg in professional and ecotoxicology'. In this report we present the results of our investigations on the effect of Cd on Mg metabolism. The experiment was performed on rabbits given orally, every day, for 4 weeks 10 mg Cd/kg b.w. as aqueous solution of CdCl 2 . Magnesium content was determined in blood, urine, soft tissues and bones by the AAS method. Under the experimental conditions, Cd lead to statistically significant decrease of blood Mg (p < 0.001 after day 16) which was associated with increased Mg elimination via urine (p < 0.01). Statistically significant changes were not detected in the tissues, except in the liver where we found enhanced Mg content (p < 0.05), while its level in the muscles decreased (p < 0.01).en
dc.publisherJohn Libbey Eurotext
dc.rightsrestrictedAccess
dc.sourceMagnesium Research
dc.subjectBlooden
dc.subjectCadmiumen
dc.subjectMagnesiumen
dc.subjectOrgansen
dc.subjectRabbitsen
dc.subjectUrineen
dc.titleContribution to interaction between magnesium and toxic metals: The effect of prolonged cadmium intoxication on magnesium metabolism in rabbitsen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractСтојановић, З; Солдатовић, Данило; Матовић, Весна; Вујановић, Драгана;
dc.citation.volume11
dc.citation.issue4
dc.citation.spage283
dc.citation.epage288
dc.citation.other11(4): 283-288
dc.citation.rankM23
dc.identifier.scopus2-s2.0-0032239827
dc.identifier.rcubhttps://hdl.handle.net/21.15107/rcub_farfar_211
dc.type.versionpublishedVersion


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