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dc.creatorMartinović, Jelena
dc.creatorDopsaj, Violeta
dc.date.accessioned2019-09-02T11:39:38Z
dc.date.available2019-09-02T11:39:38Z
dc.date.issued2014
dc.identifier.issn1820-6301
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/2123
dc.description.abstractOxidative stress, which occurs as a result of physical exercise, has been intensively investigated in the last two decades. A large number of studies have been done on humans and in animal models, which resulted in clarification of the mechanism of free radical generation during exercise. Free radicals, unstable and reactive molecules that can be involved in cellular damage, are mainly generated by the mitochondria, xanthine oxidase, and neutrophils and other phagocytes. Increased production of free radicals during exercise is followed by the enhanced activity of the endogenous antioxidant defense system, which consists of enzymes and non-enzymatic substances. Very important results of previous studies have been related to adaptation mechanisms activated in response to increased oxidative stress during exercise. In addition to mitochondrial biogenesis and synthesis of new components of the respiratory chain to match higher energy demands, adaptation to regular physical exercise involves an increased expression of genes responsible for antioxidant enzyme synthesis. Also, great attention has been paid to the use of antioxidant supplements. The importance and effect of supplementation with dietary antioxidants depend on several factors such as intensity, frequency and mode of exercise as well as on the type and dose of the antioxidants used. Applying the results of previous research and monitoring the parameters of oxidative stress and antioxidative defense could help health professionals in understanding the medical condition of the athlete.en
dc.publisherSportska akademija, Beograd
dc.rightsopenAccess
dc.sourceSerbian Journal of Sports sciences
dc.subjectFree radicalsen
dc.subjectantioxidative defenseen
dc.subjectexerciseen
dc.subjectadaptive responsesen
dc.subjectdietary antioxidantsen
dc.titleOxidative stress in athletes: From the scientific basis to practical aspectsen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractДопсај, Виолета; Мартиновић, Јелена;
dc.citation.volume8
dc.citation.issue1
dc.citation.spage11
dc.citation.epage22
dc.citation.other8(1): 11-22
dc.citation.rankM51
dc.identifier.fulltexthttp://farfar.pharmacy.bg.ac.rs//bitstream/id/853/2121.pdf
dc.identifier.rcubconv_1035
dc.type.versionpublishedVersion


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