Alkyl polyglucosides (APGs) are a perfect amphiphilic structure, with excellent surface activity and solubility feature. The aim of this study is to develop a simple system, with a relatively low emulsifier content, composed of materials mainly naturally based and with no additional fatty alcohol. Hydroxystearyl alcohol and Hydroxystearyl glucoside, prepared with Jojoba and Hazelnut oil, medium chain triglycerides with or without Xylitylglucoside and Anhydroxylitol and Xylitol, have been investigated by using microscopy, rheology, thermal analysis, pH and conductimetry. Cyclic stress and in vivo skin irritation tests were also conducted. The investigated natural APG emulsifier has a capacity to form simple and stable emulsions of desirable rheological profile with improved hydration potential and to renew damaged skin, thus it can be safely applied as stabilizer in cosmetic and prospective pharmaceutical cream-bases.
Keywords:
Alkyl polyglucoside emulsifier / rheological behavior / cyclic stress test / in vivo skin irritation test / skin hydration
TY - JOUR
AU - Bogdanović-Marković, Dragana
AU - Tasić-Kostov, Marija
AU - Lukić, Milica
AU - Isailović, Tanja
AU - Krstonosić, Veljko
AU - Daniels, Rolf
AU - Savić, Snežana
PY - 2014
UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2130
AB - Alkyl polyglucosides (APGs) are a perfect amphiphilic structure, with excellent surface activity and solubility feature. The aim of this study is to develop a simple system, with a relatively low emulsifier content, composed of materials mainly naturally based and with no additional fatty alcohol. Hydroxystearyl alcohol and Hydroxystearyl glucoside, prepared with Jojoba and Hazelnut oil, medium chain triglycerides with or without Xylitylglucoside and Anhydroxylitol and Xylitol, have been investigated by using microscopy, rheology, thermal analysis, pH and conductimetry. Cyclic stress and in vivo skin irritation tests were also conducted. The investigated natural APG emulsifier has a capacity to form simple and stable emulsions of desirable rheological profile with improved hydration potential and to renew damaged skin, thus it can be safely applied as stabilizer in cosmetic and prospective pharmaceutical cream-bases.
PB - Carl Hanser Verlag, Munich
T2 - Tenside Surfactants Detergents
T1 - Physicochemical Characterization and in vivo Skin Performance of a Novel Alkyl Polyglucoside Emulsifier in Natural Cosmetic Cream-Bases
VL - 51
IS - 2
SP - 133
EP - 145
DO - 10.3139/113.110294
ER -
@article{
author = "Bogdanović-Marković, Dragana and Tasić-Kostov, Marija and Lukić, Milica and Isailović, Tanja and Krstonosić, Veljko and Daniels, Rolf and Savić, Snežana",
year = "2014",
abstract = "Alkyl polyglucosides (APGs) are a perfect amphiphilic structure, with excellent surface activity and solubility feature. The aim of this study is to develop a simple system, with a relatively low emulsifier content, composed of materials mainly naturally based and with no additional fatty alcohol. Hydroxystearyl alcohol and Hydroxystearyl glucoside, prepared with Jojoba and Hazelnut oil, medium chain triglycerides with or without Xylitylglucoside and Anhydroxylitol and Xylitol, have been investigated by using microscopy, rheology, thermal analysis, pH and conductimetry. Cyclic stress and in vivo skin irritation tests were also conducted. The investigated natural APG emulsifier has a capacity to form simple and stable emulsions of desirable rheological profile with improved hydration potential and to renew damaged skin, thus it can be safely applied as stabilizer in cosmetic and prospective pharmaceutical cream-bases.",
publisher = "Carl Hanser Verlag, Munich",
journal = "Tenside Surfactants Detergents",
title = "Physicochemical Characterization and in vivo Skin Performance of a Novel Alkyl Polyglucoside Emulsifier in Natural Cosmetic Cream-Bases",
volume = "51",
number = "2",
pages = "133-145",
doi = "10.3139/113.110294"
}
Bogdanović-Marković, D., Tasić-Kostov, M., Lukić, M., Isailović, T., Krstonosić, V., Daniels, R.,& Savić, S.. (2014). Physicochemical Characterization and in vivo Skin Performance of a Novel Alkyl Polyglucoside Emulsifier in Natural Cosmetic Cream-Bases. in Tenside Surfactants Detergents
Carl Hanser Verlag, Munich., 51(2), 133-145.
https://doi.org/10.3139/113.110294
Bogdanović-Marković D, Tasić-Kostov M, Lukić M, Isailović T, Krstonosić V, Daniels R, Savić S. Physicochemical Characterization and in vivo Skin Performance of a Novel Alkyl Polyglucoside Emulsifier in Natural Cosmetic Cream-Bases. in Tenside Surfactants Detergents. 2014;51(2):133-145.
doi:10.3139/113.110294 .
Bogdanović-Marković, Dragana, Tasić-Kostov, Marija, Lukić, Milica, Isailović, Tanja, Krstonosić, Veljko, Daniels, Rolf, Savić, Snežana, "Physicochemical Characterization and in vivo Skin Performance of a Novel Alkyl Polyglucoside Emulsifier in Natural Cosmetic Cream-Bases" in Tenside Surfactants Detergents, 51, no. 2 (2014):133-145,
https://doi.org/10.3139/113.110294 . .
