Приказ основних података о документу
Introduction to Molecular genetic diagnostics
dc.creator | Novaković, Ivana | |
dc.creator | Maksimović, Nela | |
dc.creator | Pavlović, Aleksandra | |
dc.creator | Žarković, Milena | |
dc.creator | Rovcanin, Branislav | |
dc.creator | Mirković, Duško | |
dc.creator | Pekmezović, Tatjana | |
dc.creator | Cvetković, Dragana | |
dc.date.accessioned | 2019-09-02T11:40:16Z | |
dc.date.available | 2019-09-02T11:40:16Z | |
dc.date.issued | 2014 | |
dc.identifier.issn | 1452-8258 | |
dc.identifier.uri | https://farfar.pharmacy.bg.ac.rs/handle/123456789/2148 | |
dc.description.abstract | Molecular genetic testing is part of modern medical practice. DNA tests are an essential part of diagnostics and genetic counseling in single gene diseases, while their application in polygenic disorders is still limited. Pharmacogenetics studies DNA variants associated with variations in drug efficacy and toxicity, and tests in this field are being developed rapidly. The main method for molecular genetic testing is the polymerase chain reaction, with a number of modifications. New methods, such as next generation sequencing and DNA microarray, should allow simultaneous analysis of a number of genes, even whole genome sequencing. Ethical concerns in molecular genetic testing are very important, along with legislation. After molecular genetic testing, interpretation of results and genetic counseling should be done by professionals. With the example of thrombophilia, we discuss questions about genetic testing, its possibilities and promises. | en |
dc.publisher | Društvo medicinskih biohemičara Srbije, Beograd i Versita | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/175091/RS// | |
dc.rights | openAccess | |
dc.source | Journal of Medical Biochemistry | |
dc.subject | molecular genetics | en |
dc.subject | test | en |
dc.subject | methods | en |
dc.subject | genetic counselling | en |
dc.title | Introduction to Molecular genetic diagnostics | en |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Пекмезовић, Татјана; Новаковић, Ивана; Мирковић, Душко; Ровцанин, Бранислав; Максимовић, Нела; Цветковић, Драгана; Жарковић, Милена; Павловић, Aлександра; | |
dc.citation.volume | 33 | |
dc.citation.issue | 1 | |
dc.citation.spage | 3 | |
dc.citation.epage | 7 | |
dc.citation.other | 33(1): 3-7 | |
dc.citation.rank | M23 | |
dc.identifier.wos | 000326578500002 | |
dc.identifier.doi | 10.2478/jomb-2013-0039 | |
dc.identifier.scopus | 2-s2.0-84989205065 | |
dc.identifier.fulltext | https://farfar.pharmacy.bg.ac.rs//bitstream/id/873/2146.pdf | |
dc.type.version | publishedVersion |