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Metals and organic compounds in the biosynthesis of cannabinoids: a chemometric approach to the analysis of Cannabis sativa samples

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Authors
Radosavljević-Stevanović, Nataša
Marković, Jelena
Agatonović-Kuštrin, Snežana
Ražić, Slavica
Article (Published version)
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Abstract
Illicit production and trade of Cannabis sativa affect many societies. This drug is the most popular and easy to produce. Important information for the authorities is the production locality and the indicators of a particular production. This work is an attempt to recognise correlations between the metal content in the different parts of C. sativa L., in soils where plants were cultivated and the cannabinoids content, as a potential indicator. The organic fraction of the leaves of Cannabis plants was investigated by GC-FID analysis. In addition, the determination of Cu, Fe, Cr, Mn, Zn, Ca and Mg was realised by spectroscopic techniques (FAAS and GFAAS). In this study, numerous correlations between metal content in plants and soil, already confirmed in previous publications, were analysed applying chemometric unsupervised methods, that is, principal component analysis, factor analysis and cluster analysis, in order to highlight their role in the biosynthesis of cannabinoids.
Keywords:
cannabinoid biosynthesis / GC-FID / atomic spectrometry / chemometrics
Source:
Natural Product Research, 2014, 28, 8, 511-516
Publisher:
  • Taylor & Francis Ltd, Abingdon
Funding / projects:
  • Advanced technologies for monitoring and environmental protection from chemical pollutants and radiation burden (RS-43009)

DOI: 10.1080/14786419.2014.880912

ISSN: 1478-6419

PubMed: 24483128

WoS: 000334070700002

Scopus: 2-s2.0-84898057017
[ Google Scholar ]
3
3
URI
https://farfar.pharmacy.bg.ac.rs/handle/123456789/2163
Collections
  • Radovi istraživača / Researchers’ publications
Institution/Community
Pharmacy
TY  - JOUR
AU  - Radosavljević-Stevanović, Nataša
AU  - Marković, Jelena
AU  - Agatonović-Kuštrin, Snežana
AU  - Ražić, Slavica
PY  - 2014
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2163
AB  - Illicit production and trade of Cannabis sativa affect many societies. This drug is the most popular and easy to produce. Important information for the authorities is the production locality and the indicators of a particular production. This work is an attempt to recognise correlations between the metal content in the different parts of C. sativa L., in soils where plants were cultivated and the cannabinoids content, as a potential indicator. The organic fraction of the leaves of Cannabis plants was investigated by GC-FID analysis. In addition, the determination of Cu, Fe, Cr, Mn, Zn, Ca and Mg was realised by spectroscopic techniques (FAAS and GFAAS). In this study, numerous correlations between metal content in plants and soil, already confirmed in previous publications, were analysed applying chemometric unsupervised methods, that is, principal component analysis, factor analysis and cluster analysis, in order to highlight their role in the biosynthesis of cannabinoids.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Natural Product Research
T1  - Metals and organic compounds in the biosynthesis of cannabinoids: a chemometric approach to the analysis of Cannabis sativa samples
VL  - 28
IS  - 8
SP  - 511
EP  - 516
DO  - 10.1080/14786419.2014.880912
ER  - 
@article{
author = "Radosavljević-Stevanović, Nataša and Marković, Jelena and Agatonović-Kuštrin, Snežana and Ražić, Slavica",
year = "2014",
abstract = "Illicit production and trade of Cannabis sativa affect many societies. This drug is the most popular and easy to produce. Important information for the authorities is the production locality and the indicators of a particular production. This work is an attempt to recognise correlations between the metal content in the different parts of C. sativa L., in soils where plants were cultivated and the cannabinoids content, as a potential indicator. The organic fraction of the leaves of Cannabis plants was investigated by GC-FID analysis. In addition, the determination of Cu, Fe, Cr, Mn, Zn, Ca and Mg was realised by spectroscopic techniques (FAAS and GFAAS). In this study, numerous correlations between metal content in plants and soil, already confirmed in previous publications, were analysed applying chemometric unsupervised methods, that is, principal component analysis, factor analysis and cluster analysis, in order to highlight their role in the biosynthesis of cannabinoids.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Natural Product Research",
title = "Metals and organic compounds in the biosynthesis of cannabinoids: a chemometric approach to the analysis of Cannabis sativa samples",
volume = "28",
number = "8",
pages = "511-516",
doi = "10.1080/14786419.2014.880912"
}
Radosavljević-Stevanović, N., Marković, J., Agatonović-Kuštrin, S.,& Ražić, S.. (2014). Metals and organic compounds in the biosynthesis of cannabinoids: a chemometric approach to the analysis of Cannabis sativa samples. in Natural Product Research
Taylor & Francis Ltd, Abingdon., 28(8), 511-516.
https://doi.org/10.1080/14786419.2014.880912
Radosavljević-Stevanović N, Marković J, Agatonović-Kuštrin S, Ražić S. Metals and organic compounds in the biosynthesis of cannabinoids: a chemometric approach to the analysis of Cannabis sativa samples. in Natural Product Research. 2014;28(8):511-516.
doi:10.1080/14786419.2014.880912 .
Radosavljević-Stevanović, Nataša, Marković, Jelena, Agatonović-Kuštrin, Snežana, Ražić, Slavica, "Metals and organic compounds in the biosynthesis of cannabinoids: a chemometric approach to the analysis of Cannabis sativa samples" in Natural Product Research, 28, no. 8 (2014):511-516,
https://doi.org/10.1080/14786419.2014.880912 . .

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