Metals and organic compounds in the biosynthesis of cannabinoids: a chemometric approach to the analysis of Cannabis sativa samples
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Radosavljević-Stevanović, NatašaMarković, Jelena

Agatonović-Kuštrin, Snežana

Ražić, Slavica

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Illicit production and trade of Cannabis sativa affect many societies. This drug is the most popular and easy to produce. Important information for the authorities is the production locality and the indicators of a particular production. This work is an attempt to recognise correlations between the metal content in the different parts of C. sativa L., in soils where plants were cultivated and the cannabinoids content, as a potential indicator. The organic fraction of the leaves of Cannabis plants was investigated by GC-FID analysis. In addition, the determination of Cu, Fe, Cr, Mn, Zn, Ca and Mg was realised by spectroscopic techniques (FAAS and GFAAS). In this study, numerous correlations between metal content in plants and soil, already confirmed in previous publications, were analysed applying chemometric unsupervised methods, that is, principal component analysis, factor analysis and cluster analysis, in order to highlight their role in the biosynthesis of cannabinoids.
Keywords:
cannabinoid biosynthesis / GC-FID / atomic spectrometry / chemometricsSource:
Natural Product Research, 2014, 28, 8, 511-516Publisher:
- Taylor & Francis Ltd, Abingdon
Funding / projects:
DOI: 10.1080/14786419.2014.880912
ISSN: 1478-6419
PubMed: 24483128
WoS: 000334070700002
Scopus: 2-s2.0-84898057017
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PharmacyTY - JOUR AU - Radosavljević-Stevanović, Nataša AU - Marković, Jelena AU - Agatonović-Kuštrin, Snežana AU - Ražić, Slavica PY - 2014 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2163 AB - Illicit production and trade of Cannabis sativa affect many societies. This drug is the most popular and easy to produce. Important information for the authorities is the production locality and the indicators of a particular production. This work is an attempt to recognise correlations between the metal content in the different parts of C. sativa L., in soils where plants were cultivated and the cannabinoids content, as a potential indicator. The organic fraction of the leaves of Cannabis plants was investigated by GC-FID analysis. In addition, the determination of Cu, Fe, Cr, Mn, Zn, Ca and Mg was realised by spectroscopic techniques (FAAS and GFAAS). In this study, numerous correlations between metal content in plants and soil, already confirmed in previous publications, were analysed applying chemometric unsupervised methods, that is, principal component analysis, factor analysis and cluster analysis, in order to highlight their role in the biosynthesis of cannabinoids. PB - Taylor & Francis Ltd, Abingdon T2 - Natural Product Research T1 - Metals and organic compounds in the biosynthesis of cannabinoids: a chemometric approach to the analysis of Cannabis sativa samples VL - 28 IS - 8 SP - 511 EP - 516 DO - 10.1080/14786419.2014.880912 ER -
@article{ author = "Radosavljević-Stevanović, Nataša and Marković, Jelena and Agatonović-Kuštrin, Snežana and Ražić, Slavica", year = "2014", abstract = "Illicit production and trade of Cannabis sativa affect many societies. This drug is the most popular and easy to produce. Important information for the authorities is the production locality and the indicators of a particular production. This work is an attempt to recognise correlations between the metal content in the different parts of C. sativa L., in soils where plants were cultivated and the cannabinoids content, as a potential indicator. The organic fraction of the leaves of Cannabis plants was investigated by GC-FID analysis. In addition, the determination of Cu, Fe, Cr, Mn, Zn, Ca and Mg was realised by spectroscopic techniques (FAAS and GFAAS). In this study, numerous correlations between metal content in plants and soil, already confirmed in previous publications, were analysed applying chemometric unsupervised methods, that is, principal component analysis, factor analysis and cluster analysis, in order to highlight their role in the biosynthesis of cannabinoids.", publisher = "Taylor & Francis Ltd, Abingdon", journal = "Natural Product Research", title = "Metals and organic compounds in the biosynthesis of cannabinoids: a chemometric approach to the analysis of Cannabis sativa samples", volume = "28", number = "8", pages = "511-516", doi = "10.1080/14786419.2014.880912" }
Radosavljević-Stevanović, N., Marković, J., Agatonović-Kuštrin, S.,& Ražić, S.. (2014). Metals and organic compounds in the biosynthesis of cannabinoids: a chemometric approach to the analysis of Cannabis sativa samples. in Natural Product Research Taylor & Francis Ltd, Abingdon., 28(8), 511-516. https://doi.org/10.1080/14786419.2014.880912
Radosavljević-Stevanović N, Marković J, Agatonović-Kuštrin S, Ražić S. Metals and organic compounds in the biosynthesis of cannabinoids: a chemometric approach to the analysis of Cannabis sativa samples. in Natural Product Research. 2014;28(8):511-516. doi:10.1080/14786419.2014.880912 .
Radosavljević-Stevanović, Nataša, Marković, Jelena, Agatonović-Kuštrin, Snežana, Ražić, Slavica, "Metals and organic compounds in the biosynthesis of cannabinoids: a chemometric approach to the analysis of Cannabis sativa samples" in Natural Product Research, 28, no. 8 (2014):511-516, https://doi.org/10.1080/14786419.2014.880912 . .