Two copies of bla (NDM-1) gene are present in NDM-1 producing Pseudomonas aeruginosa isolates from Serbia
Само за регистроване кориснике
2014
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
New Delhi metallo-beta-lactamase producing Pseudomonas aeruginosa isolates are of special interest since P. aeruginosa is a major cause of nosocomial infections, the treatment of which could now be jeopardized, especially in developing countries. Six additional NDM-1 positive P. aeruginosa clinical isolates belonging to two different genotypes were shown to be plasmid-free. PFGE-hybridization experiments revealed the chromosomal location of the bla (NDM-1) gene. Restriction analysis and hybridization revealed that two copies of the bla (NDM-1) gene are present in the genomes of all tested isolates, as in previously characterized P. aeruginosa MMA83. Moreover, it was shown that increasing imipenem concentration did not have the effect on copy number of the bla (NDM-1) gene in the genome of P. aeruginosa MMA83.
Кључне речи:
NDM-1 / Metallo-beta-lactamase / Molecular genetics / Pseudomonas aeruginosaИзвор:
Antonie van Leeuwenhoek, International Journal of General and Molecular Microbiology, 2014, 105, 3, 613-618Издавач:
- Springer, Dordrecht
Финансирање / пројекти:
DOI: 10.1007/s10482-013-0094-z
ISSN: 0003-6072
PubMed: 24343100
WoS: 000330953700018
Scopus: 2-s2.0-84894254640
Институција/група
PharmacyTY - JOUR AU - Jovčić, Branko AU - Lepsanović, Zorica AU - Begović, Jelena AU - Filipić, Brankica AU - Kojić, Milan PY - 2014 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2173 AB - New Delhi metallo-beta-lactamase producing Pseudomonas aeruginosa isolates are of special interest since P. aeruginosa is a major cause of nosocomial infections, the treatment of which could now be jeopardized, especially in developing countries. Six additional NDM-1 positive P. aeruginosa clinical isolates belonging to two different genotypes were shown to be plasmid-free. PFGE-hybridization experiments revealed the chromosomal location of the bla (NDM-1) gene. Restriction analysis and hybridization revealed that two copies of the bla (NDM-1) gene are present in the genomes of all tested isolates, as in previously characterized P. aeruginosa MMA83. Moreover, it was shown that increasing imipenem concentration did not have the effect on copy number of the bla (NDM-1) gene in the genome of P. aeruginosa MMA83. PB - Springer, Dordrecht T2 - Antonie van Leeuwenhoek, International Journal of General and Molecular Microbiology T1 - Two copies of bla (NDM-1) gene are present in NDM-1 producing Pseudomonas aeruginosa isolates from Serbia VL - 105 IS - 3 SP - 613 EP - 618 DO - 10.1007/s10482-013-0094-z ER -
@article{ author = "Jovčić, Branko and Lepsanović, Zorica and Begović, Jelena and Filipić, Brankica and Kojić, Milan", year = "2014", abstract = "New Delhi metallo-beta-lactamase producing Pseudomonas aeruginosa isolates are of special interest since P. aeruginosa is a major cause of nosocomial infections, the treatment of which could now be jeopardized, especially in developing countries. Six additional NDM-1 positive P. aeruginosa clinical isolates belonging to two different genotypes were shown to be plasmid-free. PFGE-hybridization experiments revealed the chromosomal location of the bla (NDM-1) gene. Restriction analysis and hybridization revealed that two copies of the bla (NDM-1) gene are present in the genomes of all tested isolates, as in previously characterized P. aeruginosa MMA83. Moreover, it was shown that increasing imipenem concentration did not have the effect on copy number of the bla (NDM-1) gene in the genome of P. aeruginosa MMA83.", publisher = "Springer, Dordrecht", journal = "Antonie van Leeuwenhoek, International Journal of General and Molecular Microbiology", title = "Two copies of bla (NDM-1) gene are present in NDM-1 producing Pseudomonas aeruginosa isolates from Serbia", volume = "105", number = "3", pages = "613-618", doi = "10.1007/s10482-013-0094-z" }
Jovčić, B., Lepsanović, Z., Begović, J., Filipić, B.,& Kojić, M.. (2014). Two copies of bla (NDM-1) gene are present in NDM-1 producing Pseudomonas aeruginosa isolates from Serbia. in Antonie van Leeuwenhoek, International Journal of General and Molecular Microbiology Springer, Dordrecht., 105(3), 613-618. https://doi.org/10.1007/s10482-013-0094-z
Jovčić B, Lepsanović Z, Begović J, Filipić B, Kojić M. Two copies of bla (NDM-1) gene are present in NDM-1 producing Pseudomonas aeruginosa isolates from Serbia. in Antonie van Leeuwenhoek, International Journal of General and Molecular Microbiology. 2014;105(3):613-618. doi:10.1007/s10482-013-0094-z .
Jovčić, Branko, Lepsanović, Zorica, Begović, Jelena, Filipić, Brankica, Kojić, Milan, "Two copies of bla (NDM-1) gene are present in NDM-1 producing Pseudomonas aeruginosa isolates from Serbia" in Antonie van Leeuwenhoek, International Journal of General and Molecular Microbiology, 105, no. 3 (2014):613-618, https://doi.org/10.1007/s10482-013-0094-z . .