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dc.creatorKundaković, Tatjana
dc.creatorStanojković, Tatjana
dc.creatorKolundžija, Branka
dc.creatorMarković, Stevan
dc.creatorŠukilović, Branka
dc.creatorMilenković, Marina
dc.creatorLakušić, Branislava
dc.date.accessioned2019-09-02T11:42:01Z
dc.date.available2019-09-02T11:42:01Z
dc.date.issued2014
dc.identifier.issn1934-578X
dc.identifier.urihttps://farfar.pharmacy.bg.ac.rs/handle/123456789/2217
dc.description.abstractThe antimicrobial and cytotoxic activities of the essential oil of Satureja montana ssp. pisidica from two localities (mountains Korab and Galicica) were studied. Forty-nine components were identified in the each sample. Oxygenated monoterpene hydrocarbons were the major compounds: carvacrol, thymol, carvacrol methyl ether and beta-linalool. Both tested essential oils showed very high and similar antimicrobial activity. Minimal inhibitory concentrations ranged from 12.5 mu g/mL against S. epidermidis to 50 mu g/mL against P. aerugmosa and C. albicans. The cytotoxic effect of the essential oils was tested against MDA-MB-361, MDA-MB-453, HeLa, LS174 and MRCS cells. The essential oil from Korab demonstrated significantly better results than the oil from Galicica, particularly against HeLa and MDA-MB-453 cell lines, with IC50 values of 63.5 and 72.3 mu g/mL, while the oil from Galicica was the most active on the human epithelial cervical cancer HeLa cells (IC50 99.7 mu g/mL).en
dc.publisherSage Publications Inc, Thousand Oaks
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173021/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/175011/RS//
dc.rightsopenAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/
dc.sourceNatural Product Communications
dc.subjectSatureja montana ssp pisidicaen
dc.subjectEssential oilen
dc.subjectCytotoxicityen
dc.subjectAntimicrobial activityen
dc.subjectCarvacrolen
dc.titleCytotoxicity and Antimicrobial Activity of the Essential Oil from Satureja montana subsp pisidica (Lamiceae)en
dc.typearticle
dc.rights.licenseBY-NC
dcterms.abstractКолунджија, Бранка; Станојковић, Татјана; Миленковић, Марина; Кундаковић, Татјана; Марковић, Стеван; Сукиловић, Бранка; Лакушић, Бранислава;
dc.citation.volume9
dc.citation.issue4
dc.citation.spage569
dc.citation.epage572
dc.citation.other9(4): 569-572
dc.citation.rankM23
dc.identifier.wos000335083500037
dc.identifier.pmid24868886
dc.identifier.scopus2-s2.0-84898802085
dc.identifier.fulltexthttps://farfar.pharmacy.bg.ac.rs/bitstream/id/7334/Cytotoxicity_Antimicrobial_Activity_pub_2014.pdf
dc.identifier.rcubhttps://hdl.handle.net/21.15107/rcub_farfar_2217
dc.type.versionpublishedVersion


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