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dc.creatorVidović, Bojana
dc.creatorStefanović, Aleksandra
dc.creatorMilovanović, Srđan
dc.creatorĐorđević, Brižita
dc.creatorKotur-Stevuljević, Jelena
dc.creatorIvanišević, Jasmina
dc.creatorMiljković, Milica
dc.creatorSpasić, Slavica
dc.date.accessioned2019-09-02T11:42:24Z
dc.date.available2019-09-02T11:42:24Z
dc.date.issued2014
dc.identifier.issn0036-5513
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/2230
dc.description.abstractBackground. The purpose of this study was to assess oxidative stress status parameters and their possible associations with traditional cardiovascular risk factors in patients with schizophrenia, as well as their potential for patient-control discrimination. Methods. Fasting glucose, lipid profi le and oxidative stress status parameters were assessed in 30 schizophrenic patients with atypical antipsychotic therapy and 60 control subjects. Results. Malondialdehyde (MDA), pro-oxidant/antioxidant balance (PAB) and total anti-oxidant status (TAS) were significantly higher whereas total sulfhydryl (SH) groups were significantly lower in schizophrenic patients vs. control group. Higher serum PAB values showed an independent association with schizophrenia. The addition of PAB to conventional risk factors improved discrimination between healthy control subjects and patients. Conclusion. Increased oxidative stress and changed lipid profi le parameters are associated in schizophrenic patients and may indicate risk for atherosclerosis. The serum PAB level may reflect the levels of oxidative stress in schizophrenia and improve discrimination of patients from controls.en
dc.publisherInforma Healthcare, London
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/175035/RS//
dc.rightsrestrictedAccess
dc.sourceScandinavian Journal of Clinical and Laboratory Investigation
dc.subjectOverweighten
dc.subjectcardiovascular diseaseen
dc.subjectantioxidative capacityen
dc.subjectlipidsen
dc.subjectantipsychotic treatmenten
dc.titleAssociations of oxidative stress status parameters with traditional cardiovascular disease risk factors in patients with schizophreniaen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractКотур-Стевуљевић, Јелена; Стефановић, Aлександра; Миловановић, Срђан; Миљковић, Милица; Спасић, Славица; Ђорђевић, Брижита; Иванишевић, Јасмина; Видовић, Бојана;
dc.citation.volume74
dc.citation.issue3
dc.citation.spage184
dc.citation.epage191
dc.citation.other74(3): 184-191
dc.citation.rankM23
dc.identifier.wos000334738200002
dc.identifier.doi10.3109/00365513.2013.873947
dc.identifier.pmid24446766
dc.identifier.scopus2-s2.0-84898459914
dc.identifier.rcubconv_3065
dc.type.versionpublishedVersion


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