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dc.creatorTasić-Kostov, Marija
dc.creatorVesić, Sonja
dc.creatorSavić, Snežana
dc.date.accessioned2019-09-02T11:43:08Z
dc.date.available2019-09-02T11:43:08Z
dc.date.issued2014
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/2258
dc.description.abstractEmulsion systems are the most common vehicles for topical drugs/cosmetic actives. Absence of skin irritation potential is an important legislative requirement. Overcoming emulsion irritancy is usually achieved by selection of emulsifiers. Alkyl Polyglucoside (APG) emulsifiers, successfully used in cosmetics and popularly labelled as skin- and environmentally friendly, have attracted considerable interest. Non-invasive measurements of biophysical skin parameters, and approved in vitro methods, are used for reliable and objective determination of skin properties. This chapter discusses assessment of the performance of topical emulsions, particularly those based on APG-mixed emulsifiers, and interpretation of the results. Research into the safety and efficacy of APGs indicates that APG surfactants could be used for tailoring mild emulsion vehicles, showing benefits as carriers for actives with an unfavourable skin irritation profile.en
dc.publisherElsevier Inc.
dc.rightsrestrictedAccess
dc.sourceAlkyl Polyglucosides: From Natural-Origin Surfactants to Prospective Delivery Systems
dc.subjectAlkyl Polyglucoside mixed emulsifiersen
dc.subjectBiophysical skin parametersen
dc.subjectIn vivo/in vitro skin safety and efficacyen
dc.subjectMoisturizing cosmetic activesen
dc.subjectPharmaceutical and cosmetic emulsion-type topical proen
dc.titleObjective skin performance evaluation: How mild are APGs to the skin?en
dc.typebookPart
dc.rights.licenseARR
dcterms.abstractТасић-Костов, Марија; Савић, Снежана; Весић, Соња;
dc.citation.spage135
dc.citation.epage161
dc.citation.other: 135-161
dc.identifier.doi10.1533/9781908818775.135
dc.identifier.scopus2-s2.0-84942880314
dc.identifier.rcubconv_4768
dc.type.versionpublishedVersion


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