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dc.creatorMilić, Jela
dc.creatorDaković, Aleksandra
dc.creatorKrajišnik, Danina
dc.creatorRottinghaus, George E.
dc.date.accessioned2019-09-02T11:43:08Z
dc.date.available2019-09-02T11:43:08Z
dc.date.issued2014
dc.identifier.urihttps://farfar.pharmacy.bg.ac.rs/handle/123456789/2259
dc.description.abstractNatural and synthetic zeolites have emerged as potential materials for biomedical application in recent years. Zeolites are hydrated microporous tektoaluminosilicates consisting of three-dimensional frameworks of SiO4 and AlO4 tetrahedra linked through shared oxygen atoms. Clinoptilolite, a mineral from the heulandite group of zeolites, ((Na,K)6(Al6Si3O)O72·nH2O), is the most abundant sedimentary zeolite in nature. In this chapter an overview of surface modifi cation of clinoptilolite by interaction with cationic surfactants is given alongside with the methods used for characterization of the surfactant modifi ed zeolites (organozeolites/composites). Diff erent organozeolites were tested under conditions for adsorption of several mycotoxins commonly found in animal feed. Study of in vitro surfactant desorption in vitro followed by in vivo acute toxicity testing was used to demonstrate the nontoxic nature of these improved mineral materials. Functionality related characteristics of modifi ed natural zeolites were analyzed for investigation of their potential use as pharmaceutical excipients for modifi ed release of active pharmaceutical ingredients.en
dc.publisherWiley Blackwell
dc.relationinfo:eu-repo/grantAgreement/MESTD/Technological Development (TD or TR)/34031/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172018/RS//
dc.rightsrestrictedAccess
dc.sourceAdvanced Healthcare Materials
dc.subjectAdsorptionen
dc.subjectCationic surfactanten
dc.subjectClinoptiloliteen
dc.subjectDrugsen
dc.subjectFunctionality related characteristicsen
dc.subjectMycotoxinsen
dc.subjectOrganozeolites/compositesen
dc.subjectPharmaceutical excipientsen
dc.titleModified Natural Zeolites-Functional Characterization and Biomedical Applicationen
dc.typebookPart
dc.rights.licenseARR
dcterms.abstractКрајишник, Данина; Милић, Јела; Даковић, Aлександра; Роттингхаус, Георге Е.;
dc.citation.spage359
dc.citation.epage403
dc.citation.other: 359-403
dc.identifier.doi10.1002/9781118774205.ch10
dc.identifier.scopus2-s2.0-84927679773
dc.identifier.rcubconv_4769
dc.type.versionpublishedVersion


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