FarFaR - Pharmacy Repository
University of Belgrade, Faculty of Pharmacy
    • English
    • Српски
    • Српски (Serbia)
  • English 
    • English
    • Serbian (Cyrillic)
    • Serbian (Latin)
  • Login
View Item 
  •   FarFaR
  • Pharmacy
  • Radovi istraživača / Researchers’ publications
  • View Item
  •   FarFaR
  • Pharmacy
  • Radovi istraživača / Researchers’ publications
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Effects of flavonoids on plasma coagulation tested in vitro by "screening tests"

No Thumbnail
Authors
Kuntić, Vesna
Filipović-Ljesković, L
Malešev, Dušan
Jelić, S
Article (Published version)
Metadata
Show full item record
Abstract
The effects of four flavonoids: rutin, quercetin, morin and hesperidin on plasma coagulation has been examined by measuring aPTT, TT and PT. It is found that water solution of these flavonoids shows no effects in the measured quantities. This is due to their low solubility in water, and therefore, their low concentrations. Ethanolic solutions of these studied flavonoids, however, show significant prolongation of all measured coagulation times, but compared to ethanol alone, their anticoagulant effects are smaller. It is suggested that the observed effects can be attributed to the interaction of flavonoids with human plasma proteins.
Source:
Jugoslovenska medicinska biohemija, 1999, 18, 4, 167-169
Publisher:
  • Društvo medicinskih biohemičara Srbije i Crne Gore, Beograd i Univerzitet u Beogradu - Farmaceutski fakultet, Beograd

ISSN: 0354-3447

WoS: 000084404300006

[ Google Scholar ]
1
Handle
https://hdl.handle.net/21.15107/rcub_farfar_227
URI
https://farfar.pharmacy.bg.ac.rs/handle/123456789/227
Collections
  • Radovi istraživača / Researchers’ publications
Institution/Community
Pharmacy
TY  - JOUR
AU  - Kuntić, Vesna
AU  - Filipović-Ljesković, L
AU  - Malešev, Dušan
AU  - Jelić, S
PY  - 1999
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/227
AB  - The effects of four flavonoids: rutin, quercetin, morin and hesperidin on plasma coagulation has been examined by measuring aPTT, TT and PT. It is found that water solution of these flavonoids shows no effects in the measured quantities. This is due to their low solubility in water, and therefore, their low concentrations. Ethanolic solutions of these studied flavonoids, however, show significant prolongation of all measured coagulation times, but compared to ethanol alone, their anticoagulant effects are smaller. It is suggested that the observed effects can be attributed to the interaction of flavonoids with human plasma proteins.
PB  - Društvo medicinskih biohemičara Srbije i Crne Gore, Beograd i Univerzitet u Beogradu - Farmaceutski fakultet, Beograd
T2  - Jugoslovenska medicinska biohemija
T1  - Effects of flavonoids on plasma coagulation tested in vitro by "screening tests"
VL  - 18
IS  - 4
SP  - 167
EP  - 169
UR  - https://hdl.handle.net/21.15107/rcub_farfar_227
ER  - 
@article{
author = "Kuntić, Vesna and Filipović-Ljesković, L and Malešev, Dušan and Jelić, S",
year = "1999",
abstract = "The effects of four flavonoids: rutin, quercetin, morin and hesperidin on plasma coagulation has been examined by measuring aPTT, TT and PT. It is found that water solution of these flavonoids shows no effects in the measured quantities. This is due to their low solubility in water, and therefore, their low concentrations. Ethanolic solutions of these studied flavonoids, however, show significant prolongation of all measured coagulation times, but compared to ethanol alone, their anticoagulant effects are smaller. It is suggested that the observed effects can be attributed to the interaction of flavonoids with human plasma proteins.",
publisher = "Društvo medicinskih biohemičara Srbije i Crne Gore, Beograd i Univerzitet u Beogradu - Farmaceutski fakultet, Beograd",
journal = "Jugoslovenska medicinska biohemija",
title = "Effects of flavonoids on plasma coagulation tested in vitro by "screening tests"",
volume = "18",
number = "4",
pages = "167-169",
url = "https://hdl.handle.net/21.15107/rcub_farfar_227"
}
Kuntić, V., Filipović-Ljesković, L., Malešev, D.,& Jelić, S.. (1999). Effects of flavonoids on plasma coagulation tested in vitro by "screening tests". in Jugoslovenska medicinska biohemija
Društvo medicinskih biohemičara Srbije i Crne Gore, Beograd i Univerzitet u Beogradu - Farmaceutski fakultet, Beograd., 18(4), 167-169.
https://hdl.handle.net/21.15107/rcub_farfar_227
Kuntić V, Filipović-Ljesković L, Malešev D, Jelić S. Effects of flavonoids on plasma coagulation tested in vitro by "screening tests". in Jugoslovenska medicinska biohemija. 1999;18(4):167-169.
https://hdl.handle.net/21.15107/rcub_farfar_227 .
Kuntić, Vesna, Filipović-Ljesković, L, Malešev, Dušan, Jelić, S, "Effects of flavonoids on plasma coagulation tested in vitro by "screening tests"" in Jugoslovenska medicinska biohemija, 18, no. 4 (1999):167-169,
https://hdl.handle.net/21.15107/rcub_farfar_227 .

DSpace software copyright © 2002-2015  DuraSpace
About FarFaR - Pharmacy Repository | Send Feedback

OpenAIRERCUB
 

 

All of DSpaceCommunitiesAuthorsTitlesSubjectsThis institutionAuthorsTitlesSubjects

Statistics

View Usage Statistics

DSpace software copyright © 2002-2015  DuraSpace
About FarFaR - Pharmacy Repository | Send Feedback

OpenAIRERCUB