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dc.creatorPopović, Višnja
dc.creatorPetrović, Silvana
dc.creatorMilenković, Marina
dc.creatorDrobac, Milica
dc.creatorCouladis, Maria
dc.creatorNiketić, Marjan
dc.date.accessioned2019-09-02T11:47:14Z
dc.date.available2019-09-02T11:47:14Z
dc.date.issued2015
dc.identifier.issn1612-1872
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/2409
dc.description.abstractThe chemical composition and antimicrobial activity of essential oils of Laserpitium latifolium and L. ochridanum were investigated. The essential oils were isolated by steam distillation and characterized by GC-FID and GC/MS analyses. All essential oils were distinguished by high contents of monoterpenes, and alpha-pinene was the most abundant compound in the essential oils of L. latifolium underground parts and fruits (contents of 44.4 and 44.0%, resp.). The fruit essential oil was also rich in sabinene (26.8%). Regarding the L. ochridanum essential oils, the main constituents were limonene in the fruit oil (57.7%) and sabinene in the herb oil (25.9%). The antimicrobial activity of these essential oils as well as that of L. ochridanum underground parts, whose composition was reported previously, was tested by the broth-microdilution method against four Gram-positive and three Gram-negative bacteria and two Candida albicans strains. Except the L. latifolium underground-parts essential oil, the other investigated oils showed a high antimicrobial potential against Staphylococcus aureus, S. epidermidis, Micrococcus luteus, or Candida albicans (minimal inhibitory concentrations of 13.0-73.0 mu g/ml), comparable to or even higher than that of thymol, which was used as reference compound.en
dc.publisherWiley-VCH Verlag GMBH, Weinheim
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173021/RS//
dc.rightsrestrictedAccess
dc.sourceChemistry & Biodiversity
dc.titleComposition and Antimicrobial Activity of the Essential Oils of Laserpitium latifolium L. and L. ochridanum MICEVSKI (Apiaceae)en
dc.typearticle
dc.rights.licenseARR
dcterms.abstractНикетић, Марјан; Миленковић, Марина; Петровић, Силвана; Поповић, Вишња; Дробац, Милица; Цоуладис, Мариа;
dc.citation.volume12
dc.citation.issue1
dc.citation.spage170
dc.citation.epage177
dc.citation.other12(1): 170-177
dc.citation.rankM22
dc.identifier.wos000347837200010
dc.identifier.doi10.1002/cbdv.201400127
dc.identifier.pmid25641845
dc.identifier.scopus2-s2.0-84941097379
dc.identifier.rcubconv_3245
dc.type.versionpublishedVersion


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