Show simple item record

dc.creatorBajić, Vladan
dc.creatorPotparević, Biljana
dc.creatorŽivković, Lada
dc.creatorSudar, Emina
dc.creatorZafirović, Sonja
dc.creatorObradović, Milan
dc.creatorIsenović, Esma
dc.date.accessioned2019-09-02T11:48:11Z
dc.date.available2019-09-02T11:48:11Z
dc.date.issued2015
dc.identifier.issn1570-1808
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/2446
dc.description.abstractAlzheimer's disease (AD) is a multi factorial disease, related to the loss of neurons and synapses in cerebral cortex and subcortical structures, leading to degenerative changes and atrophy. Despite abundance of facts related to AD and its pathology, the only drugs used in the prevention and treatment are those from the cholinesterase inhibitors group. However, there is growing evidence that a non-classical therapeutic approach in the treatment of AD has beneficial effects. In this review we summarized recent literature data related to the non-classical drugs for the treatment of AD predominantly used in clinical testing, such as amyloid aggregation inhibitors, beta-sheet breakers, antioxidants, estrogens and immunotherapeutics.en
dc.publisherBentham Science Publ Ltd, Sharjah
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173033/RS//
dc.rightsrestrictedAccess
dc.sourceLetters in Drug Design and Discovery
dc.subjectAmyloid aggregation inhibitorsen
dc.subjectantioxidantsen
dc.subjectbeta-sheet breakersen
dc.subjectestrogensen
dc.subjectimmunotherapeutic Abetaen
dc.subjectneurode-generationen
dc.titleNon-Classical Therapeutic Approach in the Treatment of Alzheimer's Disease: A Mini Reviewen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractСудар, Емина; Зафировић, Соња; Потпаревић, Биљана; Бајић, Владан; Обрадовић, Милан; Исеновић, Есма; Живковић, Лада;
dc.citation.volume12
dc.citation.issue2
dc.citation.spage158
dc.citation.epage164
dc.citation.other12(2): 158-164
dc.citation.rankM23
dc.identifier.wos000349456200011
dc.identifier.scopus2-s2.0-84925457147
dc.identifier.rcubconv_3264
dc.type.versionpublishedVersion


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record