Rational use of antibiotics in stationary health care institution: Case study

Abstract

Between 25% and 50% of hospitalized patients receive antibiotics. Some studies estimate that 25-68% of hospital antibiotic prescribing is suboptimal. The aim of this study was to analyse antibiotic use in Medical Center 'Bežanijska Kosa'. For the period 2008-2012, yearly data on antibiotic use in inpatients were obtained from the database of the hospital pharmacy and expressed as DDD per 100 bed-days. The total antibiotic use varied during the study period from 62,3 to 65,6 DDD per 100 bed-days. The most frequently used antibiotics were cephalosporins, followed by fluoroquinolones, penicillins and aminoglycosides. Ceftriaxone was the most frequently prescribed antibiotic. The findings emphasize the need for effective measures to reduce widespread antibiotic misusage in hospitals.

Između 25% i 50 % hospitalizovanih pacijenata prima antibiotike. Neke studije procenjuju da je 25-68% antibiotika u Bolnicama propisano neadekvatno. Cilj ovog rada je bio da se Analizira upotreba antibiotika u Kliničko-bolničkom centru 'Bežanijska kosa'. Za period od 2008. do 2012. godine podaci o upotrebi antibiotika na godišnjem nivou su dobijeni iz baze podataka bolničke apoteke i izraženi kao DDD/100 postelja/dan. U toku petogodišnjeg perioda praćenja, ukupna upotreba antibiotika se kretala od 62,3do 65,6 DDD/100 postelja/dan. Najčešće propisivani antibiotici su bili cefalosporini, a zatim fluorohinoloni, penicilini i aminoglikozidi. Ceftriakson je bio najčešće propisivani antibiotik. Ovi rezultati ističu potrebu za sprovođenjem efikasnih mera kako bi se smanjila široko rasprostranjena neadekvatna upotreba antibiotika u stacionarnim zdravstvenim ustanovama.