The antibacterial activity of cyclohexane, dichlormethane, methanol and aqueous extracts of tinder fungus Fomes fomentarius (L) Fr (Polyporaceae) was tested against 9 bacterial strains (Staphylococcus aureus, Staphylococcus epidermidis, Micrococcus luteus, Bacillus subtilis, Enterococcus feacalis, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella abony), as well as against 10 different clinical isolates and one reference strain of Helicobacter pylori. Minimal inhibitory concentrations (MICs) of all extracts against 9 bacterial strains were in the range of 125-250 mu g/ml. Methanol and aqueous extracts showed significant activity against H. pylori with MIC values between 4-32 mu g/ml. Also, cytotoxicity of tested extracts was significant. Aqueous extract was the most active one against HeLa cells with an IC50 8.31 +/- 1.18 mu g/ml and N87 cells with IC50 64.46 +/- 3.13 mu g/ml without any activity against normal MRC5 cell line (>200 mu g/ml).
TY - JOUR
AU - Kolundžić, Marina
AU - Groznanić, Nađa
AU - Dodevska, Margarita
AU - Milenković, Marina
AU - Sisto, Francesca
AU - Miani, Alessandro
AU - Farronato, Giampietro
AU - Kundaković, Tatjana
PY - 2016
UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2576
AB - The antibacterial activity of cyclohexane, dichlormethane, methanol and aqueous extracts of tinder fungus Fomes fomentarius (L) Fr (Polyporaceae) was tested against 9 bacterial strains (Staphylococcus aureus, Staphylococcus epidermidis, Micrococcus luteus, Bacillus subtilis, Enterococcus feacalis, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella abony), as well as against 10 different clinical isolates and one reference strain of Helicobacter pylori. Minimal inhibitory concentrations (MICs) of all extracts against 9 bacterial strains were in the range of 125-250 mu g/ml. Methanol and aqueous extracts showed significant activity against H. pylori with MIC values between 4-32 mu g/ml. Also, cytotoxicity of tested extracts was significant. Aqueous extract was the most active one against HeLa cells with an IC50 8.31 +/- 1.18 mu g/ml and N87 cells with IC50 64.46 +/- 3.13 mu g/ml without any activity against normal MRC5 cell line (>200 mu g/ml).
PB - Elsevier Science BV, Amsterdam
T2 - Industrial Crops and Products
T1 - Antibacterial and cytotoxic activities of wild mushroom Fomes fomentarius (L.) Fr., Polyporaceae
VL - 79
SP - 110
EP - 115
DO - 10.1016/j.indcrop.2015.10.030
ER -
@article{
author = "Kolundžić, Marina and Groznanić, Nađa and Dodevska, Margarita and Milenković, Marina and Sisto, Francesca and Miani, Alessandro and Farronato, Giampietro and Kundaković, Tatjana",
year = "2016",
abstract = "The antibacterial activity of cyclohexane, dichlormethane, methanol and aqueous extracts of tinder fungus Fomes fomentarius (L) Fr (Polyporaceae) was tested against 9 bacterial strains (Staphylococcus aureus, Staphylococcus epidermidis, Micrococcus luteus, Bacillus subtilis, Enterococcus feacalis, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella abony), as well as against 10 different clinical isolates and one reference strain of Helicobacter pylori. Minimal inhibitory concentrations (MICs) of all extracts against 9 bacterial strains were in the range of 125-250 mu g/ml. Methanol and aqueous extracts showed significant activity against H. pylori with MIC values between 4-32 mu g/ml. Also, cytotoxicity of tested extracts was significant. Aqueous extract was the most active one against HeLa cells with an IC50 8.31 +/- 1.18 mu g/ml and N87 cells with IC50 64.46 +/- 3.13 mu g/ml without any activity against normal MRC5 cell line (>200 mu g/ml).",
publisher = "Elsevier Science BV, Amsterdam",
journal = "Industrial Crops and Products",
title = "Antibacterial and cytotoxic activities of wild mushroom Fomes fomentarius (L.) Fr., Polyporaceae",
volume = "79",
pages = "110-115",
doi = "10.1016/j.indcrop.2015.10.030"
}
Kolundžić, M., Groznanić, N., Dodevska, M., Milenković, M., Sisto, F., Miani, A., Farronato, G.,& Kundaković, T.. (2016). Antibacterial and cytotoxic activities of wild mushroom Fomes fomentarius (L.) Fr., Polyporaceae. in Industrial Crops and Products
Elsevier Science BV, Amsterdam., 79, 110-115.
https://doi.org/10.1016/j.indcrop.2015.10.030
Kolundžić M, Groznanić N, Dodevska M, Milenković M, Sisto F, Miani A, Farronato G, Kundaković T. Antibacterial and cytotoxic activities of wild mushroom Fomes fomentarius (L.) Fr., Polyporaceae. in Industrial Crops and Products. 2016;79:110-115.
doi:10.1016/j.indcrop.2015.10.030 .
Kolundžić, Marina, Groznanić, Nađa, Dodevska, Margarita, Milenković, Marina, Sisto, Francesca, Miani, Alessandro, Farronato, Giampietro, Kundaković, Tatjana, "Antibacterial and cytotoxic activities of wild mushroom Fomes fomentarius (L.) Fr., Polyporaceae" in Industrial Crops and Products, 79 (2016):110-115,
https://doi.org/10.1016/j.indcrop.2015.10.030 . .
