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dc.creatorDzelajlija, Darko D.
dc.creatorSpasić, Slavica S.
dc.creatorKotur-Stevuljević, Jelena
dc.creatorBogavac-Stanojević, Nataša
dc.date.accessioned2019-09-02T11:53:08Z
dc.date.available2019-09-02T11:53:08Z
dc.date.issued2016
dc.identifier.issn1452-8258
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/2632
dc.description.abstractBackground: Atherosclerosis is a chronic inflammatory disease which starts early in life and depends on many factors, an important one being dyslipoproteinemia. According to several studies, atherosclerotic plaques or their precursors could be seen in children younger than 10 years. During later life, interaction with a sedentary way of life, as well as unhealthy nutrition, smoking, alcohol consumption, obesity and family history of cardiovascular disease cause the burden of atherosclerotic disease. Methods: Study included 624 children (316 boys, 308 girls), aged from 7-13 years. We analysed socio-demographic data (BMI, blood pressure, cardiovascular family history, smoking status), as well as lipid status with lipoprotein little a-Lp(a), and apolipoproteins: Apo AI, Apo B-100 for all children. This enabled us to calculate new atherogenic indices Tg/HDL-c, lipid tetrad index (LTI) and lipid pentad index (LPI). Cardiovascular risk for later life was estimated by using modified Risk Score for Young Individuals (RS), which divided the subjects according to the score level: low, medium and higher risk. Results: The older children (13 y) had better lipid status than the younger children, i.e. significantly lower total cholesterol, LDL-C, triglycerides and non-HDL-C concentration and significantly higher HDL-C concentration than the younger children and this was in accordance with the RS level. Children with a positive family history of CV disease had significantly higher Lp(a) concentration and blood pressure. LPI was significantly higher in children with a higher RS. Conclusions: The results of our work could be used for cardiovascular risk assessment in apparently healthy children to provide preventive measures which could control the change able risk factors.en
dc.publisherDruštvo medicinskih biohemičara Srbije, Beograd i Versita
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/175035/RS//
dc.rightsopenAccess
dc.sourceJournal of Medical Biochemistry
dc.titleCardiovascular risk factors in 7-13 years old children from Vojvodina (Serbia)en
dc.typearticle
dc.rights.licenseARR
dcterms.abstractДзелајлија, Дарко Д.; Богавац-Станојевић, Наташа; Котур-Стевуљевић, Јелена; Спасић, Славица С.;
dc.citation.volume35
dc.citation.issue3
dc.citation.spage293
dc.citation.epage301
dc.citation.other35(3): 293-301
dc.citation.rankM23
dc.identifier.wos000379520000003
dc.identifier.doi10.1515/jomb-2016-0006
dc.identifier.pmid28356880
dc.identifier.scopus2-s2.0-84978887272
dc.identifier.fulltexthttp://farfar.pharmacy.bg.ac.rs//bitstream/id/1311/2630.pdf
dc.identifier.rcubconv_3617
dc.type.versionpublishedVersion


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