A novel thiourea type organocatalyst possessing a single NH functionality
Само за регистроване кориснике
2016
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
A novel thiourea organocatalyst was rationally designed by altering a typical H-bonding pattern of thiourea derivatives and utilising the potential of the 3,5-bis(trifluoromethyl) phenyl motif to participate in the H-bond formation. This unique catalyst afforded the products of the alpha-amination and Michael reaction in excellent yields and with a high level of stereoselectivity. Although additional studies are necessary to establish the full potential of the catalyst and to broaden its application further, the presented results may indicate alternative routes for further exploration of the thiourea class of organocatalysts.
Извор:
Organic & Biomolecular Chemistry, 2016, 14, 28, 6712-6719Издавач:
- Royal Soc Chemistry, Cambridge
Финансирање / пројекти:
DOI: 10.1039/c6ob00387g
ISSN: 1477-0520
PubMed: 27314255
WoS: 000379432600011
Scopus: 2-s2.0-84978828212
Институција/група
PharmacyTY - JOUR AU - Jovanović, Predrag AU - Petković, Miloš AU - Simić, Milena AU - Ivković, Branka AU - Savić, Vladimir PY - 2016 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2647 AB - A novel thiourea organocatalyst was rationally designed by altering a typical H-bonding pattern of thiourea derivatives and utilising the potential of the 3,5-bis(trifluoromethyl) phenyl motif to participate in the H-bond formation. This unique catalyst afforded the products of the alpha-amination and Michael reaction in excellent yields and with a high level of stereoselectivity. Although additional studies are necessary to establish the full potential of the catalyst and to broaden its application further, the presented results may indicate alternative routes for further exploration of the thiourea class of organocatalysts. PB - Royal Soc Chemistry, Cambridge T2 - Organic & Biomolecular Chemistry T1 - A novel thiourea type organocatalyst possessing a single NH functionality VL - 14 IS - 28 SP - 6712 EP - 6719 DO - 10.1039/c6ob00387g ER -
@article{ author = "Jovanović, Predrag and Petković, Miloš and Simić, Milena and Ivković, Branka and Savić, Vladimir", year = "2016", abstract = "A novel thiourea organocatalyst was rationally designed by altering a typical H-bonding pattern of thiourea derivatives and utilising the potential of the 3,5-bis(trifluoromethyl) phenyl motif to participate in the H-bond formation. This unique catalyst afforded the products of the alpha-amination and Michael reaction in excellent yields and with a high level of stereoselectivity. Although additional studies are necessary to establish the full potential of the catalyst and to broaden its application further, the presented results may indicate alternative routes for further exploration of the thiourea class of organocatalysts.", publisher = "Royal Soc Chemistry, Cambridge", journal = "Organic & Biomolecular Chemistry", title = "A novel thiourea type organocatalyst possessing a single NH functionality", volume = "14", number = "28", pages = "6712-6719", doi = "10.1039/c6ob00387g" }
Jovanović, P., Petković, M., Simić, M., Ivković, B.,& Savić, V.. (2016). A novel thiourea type organocatalyst possessing a single NH functionality. in Organic & Biomolecular Chemistry Royal Soc Chemistry, Cambridge., 14(28), 6712-6719. https://doi.org/10.1039/c6ob00387g
Jovanović P, Petković M, Simić M, Ivković B, Savić V. A novel thiourea type organocatalyst possessing a single NH functionality. in Organic & Biomolecular Chemistry. 2016;14(28):6712-6719. doi:10.1039/c6ob00387g .
Jovanović, Predrag, Petković, Miloš, Simić, Milena, Ivković, Branka, Savić, Vladimir, "A novel thiourea type organocatalyst possessing a single NH functionality" in Organic & Biomolecular Chemistry, 14, no. 28 (2016):6712-6719, https://doi.org/10.1039/c6ob00387g . .