Приказ основних података о документу

dc.creatorMarković, Marija
dc.creatorDaković, Aleksandra
dc.creatorKrajišnik, Danina
dc.creatorKragović, Milan
dc.creatorMilić, Jela
dc.creatorLangella, Alessio
dc.creatorde Gennaro, Bruno
dc.creatorCappelletti, Piergiulio
dc.creatorMercurio, Mariano
dc.date.accessioned2019-09-02T11:54:45Z
dc.date.available2019-09-02T11:54:45Z
dc.date.issued2016
dc.identifier.issn0167-7322
dc.identifier.urihttps://farfar.pharmacy.bg.ac.rs/handle/123456789/2696
dc.description.abstractIncorporation of diclofenac sodium into phillipsite modified with cetylpyridinium chloride (CP-Cl) or hexadecyltrimethyl ammonium bromide (HDTMA-Br) was followed by batch equilibrium adsorption studies in buffer solution at pH = 7.4. Characteristics of the drug/surfactant/zeolite complexes were investigated by UV/VIS, FTIR spectroscopy, thermal (DTA/TG) analysis and-potential measurements. The obtained data confirmed that organic cations at phillipsite surface were responsible for incorporation of diclofenac sodium. Diclofenac sodium incorporated amounts increased with increasing the amount of each surfactant as well as with increasing the initial drug concentration. Langmuir model was the best model for fitting the experimental data of diclofenac adsorption on surfactant/phillipsite composites, suggesting complex adsorption mechanism. The physico-chemical properties of surfactant/phillipsite composites and enhanced incorporation of diclofenac sodium suggests that it might be possible to use these materials as drug carriers.en
dc.publisherElsevier Science BV, Amsterdam
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172018/RS//
dc.rightsrestrictedAccess
dc.sourceJournal of Molecular Liquids
dc.titleEvaluation of the surfactant/phillipsite composites as carriers for diclofenac sodiumen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractЦаппеллетти, Пиергиулио; Крајишник, Данина; Лангелла, Aлессио; Даковић, Aлександра; де Геннаро, Бруно; Милић, Јела; Мерцурио, Мариано; Краговић, Милан; Марковић, Марија;
dc.citation.volume222
dc.citation.spage711
dc.citation.epage716
dc.citation.other222: 711-716
dc.citation.rankM21
dc.identifier.wos000384784400088
dc.identifier.doi10.1016/j.molliq.2016.07.127
dc.identifier.scopus2-s2.0-84979784640
dc.type.versionpublishedVersion


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Приказ основних података о документу