Structural variations of the heterocyclic ring of the recently introduced pyrrolidine derived thiourea organocatalysts have been studied. The results showed that the stereoselectivity is highly dependent on the substitution pattern reaching a moderate level, while the yields were generally less influenced by the structural changes. The outlined results may be helpful in further exploration of the thiourea catalyst represented by structure II.
Source:
Therapeutic Advances in Drug Safety, 2016, 27, 19, 990-997
TY - JOUR
AU - Jovanović, Predrag
AU - Petković, Miloš
AU - Ivković, Branka
AU - Savić, Vladimir
PY - 2016
UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2723
AB - Structural variations of the heterocyclic ring of the recently introduced pyrrolidine derived thiourea organocatalysts have been studied. The results showed that the stereoselectivity is highly dependent on the substitution pattern reaching a moderate level, while the yields were generally less influenced by the structural changes. The outlined results may be helpful in further exploration of the thiourea catalyst represented by structure II.
PB - Pergamon-Elsevier Science Ltd, Oxford
T2 - Therapeutic Advances in Drug Safety
T1 - Pyrrolidine derived thioureas as organocatalysts in the Michael reaction of vinyl sulfone. Structure-stereoselectivity study
VL - 27
IS - 19
SP - 990
EP - 997
DO - 10.1016/j.tetasy.2016.08.004
ER -
@article{
author = "Jovanović, Predrag and Petković, Miloš and Ivković, Branka and Savić, Vladimir",
year = "2016",
abstract = "Structural variations of the heterocyclic ring of the recently introduced pyrrolidine derived thiourea organocatalysts have been studied. The results showed that the stereoselectivity is highly dependent on the substitution pattern reaching a moderate level, while the yields were generally less influenced by the structural changes. The outlined results may be helpful in further exploration of the thiourea catalyst represented by structure II.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Therapeutic Advances in Drug Safety",
title = "Pyrrolidine derived thioureas as organocatalysts in the Michael reaction of vinyl sulfone. Structure-stereoselectivity study",
volume = "27",
number = "19",
pages = "990-997",
doi = "10.1016/j.tetasy.2016.08.004"
}
Jovanović, P., Petković, M., Ivković, B.,& Savić, V.. (2016). Pyrrolidine derived thioureas as organocatalysts in the Michael reaction of vinyl sulfone. Structure-stereoselectivity study. in Therapeutic Advances in Drug Safety
Pergamon-Elsevier Science Ltd, Oxford., 27(19), 990-997.
https://doi.org/10.1016/j.tetasy.2016.08.004
Jovanović P, Petković M, Ivković B, Savić V. Pyrrolidine derived thioureas as organocatalysts in the Michael reaction of vinyl sulfone. Structure-stereoselectivity study. in Therapeutic Advances in Drug Safety. 2016;27(19):990-997.
doi:10.1016/j.tetasy.2016.08.004 .
Jovanović, Predrag, Petković, Miloš, Ivković, Branka, Savić, Vladimir, "Pyrrolidine derived thioureas as organocatalysts in the Michael reaction of vinyl sulfone. Structure-stereoselectivity study" in Therapeutic Advances in Drug Safety, 27, no. 19 (2016):990-997,
https://doi.org/10.1016/j.tetasy.2016.08.004 . .
