Pyrrolidine derived thioureas as organocatalysts in the Michael reaction of vinyl sulfone. Structure-stereoselectivity study
Authorized Users Only
Article (Published version)
MetadataShow full item record
Structural variations of the heterocyclic ring of the recently introduced pyrrolidine derived thiourea organocatalysts have been studied. The results showed that the stereoselectivity is highly dependent on the substitution pattern reaching a moderate level, while the yields were generally less influenced by the structural changes. The outlined results may be helpful in further exploration of the thiourea catalyst represented by structure II.
Source:Therapeutic Advances in Drug Safety, 2016, 27, 19, 990-997
- Pergamon-Elsevier Science Ltd, Oxford