Приказ основних података о документу

dc.creatorOmar, Eihab
dc.creatorPavlović, Ivan
dc.creatorDrobac, Milica
dc.creatorRadenković, Mirjana
dc.creatorBranković, Suzana
dc.creatorKovačević, Nada
dc.date.accessioned2019-09-02T11:55:49Z
dc.date.available2019-09-02T11:55:49Z
dc.date.issued2016
dc.identifier.issn0926-6690
dc.identifier.urihttps://farfar.pharmacy.bg.ac.rs/handle/123456789/2741
dc.description.abstractThe composition of essential oils obtained by hydrodistillation from dried stems and inflorescences of Cymbopogon nervatus (Hochst.) Chiov. (Poaceae) growing wild in Western and Eastern Sudan and collected at two different periods, was analyzed by GC and GC MS. The most dominant constituents in the oils were p-menthadienols, trans-p-mentha-1(7),8-dien-2-ol (19.9-32.6%), cis-p-mentha-1(7),8-dien-2-ol (18.9-23.3%), trans-p-mentha-2,8-dien-l-ol (10.6-21.0%) and cis-p-mentha-2,8-dien-1-ol (8.1-10.4%). The essential oil of inflorescence from the Western Sudan was tested for spasmolytic activity using three different experimental models: against spontaneous contractions, and contractions induced with ACh and KCI. The oil exhibited strong, significant and concentration-dependent spasmolytic activity. Applied in concentration of 200 mu g/ml, the oil showed 88.44 +/- 16.78% of maximal spasmolytic effect of atropine (6.4 p,,M) against spontaneous contraction. Essential oil (90 mu g/ml) inhibited ACh-induced contractions as well, and reduced the effect of the highest applied concentration of ACh to 37.29 +/- 16.16%. Additionally, the oil exhibited strong activity against contractions induced with KCI (80 mM) and in concentration of 200 mu g/ml, completely abolished the contractile effect of KCI. The essential oil of inflorescence from the Western Sudan was also tested for antioxidant activity by DPPH assay and showed moderate anti-DPPH activity (SC50 23.8 mu l/ml).en
dc.publisherElsevier Science BV, Amsterdam
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173021/RS//
dc.rightsrestrictedAccess
dc.sourceIndustrial Crops and Products
dc.titleChemical composition and spasmolytic activity of Cymbopogon nervatus (Hochst.) Chiov. (Poaceae) essential oilen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractБранковић, Сузана; Ковачевић, Нада; Омар, Еихаб; Раденковић, Мирјана; Дробац, Милица; Павловић, Иван;
dc.citation.volume91
dc.citation.spage249
dc.citation.epage254
dc.citation.other91: 249-254
dc.citation.rankM21
dc.identifier.wos000382600300029
dc.identifier.doi10.1016/j.indcrop.2016.07.013
dc.identifier.scopus2-s2.0-84984848059
dc.type.versionpublishedVersion


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Приказ основних података о документу