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dc.creatorPavun, Leposava
dc.creatorJelikić-Stankov, Milena
dc.creatorĐurđević, Predrag
dc.creatorĆirić, Andrija
dc.creatorUskoković-Marković, Snežana
dc.date.accessioned2019-09-02T11:56:11Z
dc.date.available2019-09-02T11:56:11Z
dc.date.issued2016
dc.identifier.issn1857-5552
dc.identifier.urihttps://farfar.pharmacy.bg.ac.rs/handle/123456789/2751
dc.description.abstractThe aim of this study was to develop and validate a simple, rapid, sensitive and low-cost method for determination of rutin in tablets. The proposed spectrophotometric method is based on the formation of the Zn2+-rutin complex in methanol 70% (v/v) at pH 8.52, and detection at lambda(max)= 410 nm. The concentration range over which the response was linear was 0.3-12.2 mu g ml(-1). The limit of detection (LOD) and the limit of quantification (LOQ) were 0.21 mu g ml(-1) and 0.63 mu g ml(-1), respectively. The proposed method was successfully applied to the determination of rutin in herbal dietary supplements. The reliability of the method was checked by comparison with results obtained by the established RP-HPLC/UV method. The proposed method fulfills all aimed requirements.en
dc.publisherSoc Chemists Technologists Madeconia, Skopje
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172016/RS//
dc.rightsopenAccess
dc.sourceMacedonian Journal of Chemistry and Chemical Engineering
dc.titleZinc complex-based determination of rutin in dietary supplementsen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractПавун, Лепосава; Ђурђевић, Предраг; Јеликић-Станков, Милена; Ускоковић-Марковић, Снежана; Ћирић, Aндрија;
dc.citation.volume35
dc.citation.issue1
dc.citation.spage13
dc.citation.epage18
dc.citation.other35(1): 13-18
dc.citation.rankM23
dc.identifier.wos000379376400002
dc.identifier.doi10.20450/mjcce.2016.897
dc.identifier.scopus2-s2.0-84981161237
dc.identifier.fulltexthttps://farfar.pharmacy.bg.ac.rs//bitstream/id/1395/2749.pdf
dc.type.versionpublishedVersion


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