The prevalence of obesity among adults and children worldwide has reached epic proportions and has become a major independent risk factor for the development of heart failure (HF), in addition to a contributor of hypertension and cardiovascular disease. The implications of obesity in the development of HF involve adverse effects on cardiac structure and function. Despite all of this, in the setting of chronic HF, excess body mass is associated with improved clinical outcomes, demonstrating the presence of an obesity paradox. In this review, we will discuss the gender differences, global application, potential mechanisms and role of interventions based on fitness and purposeful weight loss as potential therapeutic strategies.
TY - JOUR
AU - Parto, Parham
AU - Lavie, Carl J.
AU - Arena, Ross
AU - Bond, Samantha
AU - Popović, Dejana
AU - Ventura, Hector O.
PY - 2016
UR - http://farfar.pharmacy.bg.ac.rs/handle/123456789/2757
AB - The prevalence of obesity among adults and children worldwide has reached epic proportions and has become a major independent risk factor for the development of heart failure (HF), in addition to a contributor of hypertension and cardiovascular disease. The implications of obesity in the development of HF involve adverse effects on cardiac structure and function. Despite all of this, in the setting of chronic HF, excess body mass is associated with improved clinical outcomes, demonstrating the presence of an obesity paradox. In this review, we will discuss the gender differences, global application, potential mechanisms and role of interventions based on fitness and purposeful weight loss as potential therapeutic strategies.
PB - Future Medicine Ltd, London
T2 - Future Cardiology
T1 - Body habitus in heart failure: understanding the mechanisms and clinical significance of the obesity paradox
VL - 12
IS - 6
SP - 639
EP - 653
DO - 10.2217/fca-2016-0029
ER -
@article{
author = "Parto, Parham and Lavie, Carl J. and Arena, Ross and Bond, Samantha and Popović, Dejana and Ventura, Hector O.",
year = "2016",
url = "http://farfar.pharmacy.bg.ac.rs/handle/123456789/2757",
abstract = "The prevalence of obesity among adults and children worldwide has reached epic proportions and has become a major independent risk factor for the development of heart failure (HF), in addition to a contributor of hypertension and cardiovascular disease. The implications of obesity in the development of HF involve adverse effects on cardiac structure and function. Despite all of this, in the setting of chronic HF, excess body mass is associated with improved clinical outcomes, demonstrating the presence of an obesity paradox. In this review, we will discuss the gender differences, global application, potential mechanisms and role of interventions based on fitness and purposeful weight loss as potential therapeutic strategies.",
publisher = "Future Medicine Ltd, London",
journal = "Future Cardiology",
title = "Body habitus in heart failure: understanding the mechanisms and clinical significance of the obesity paradox",
volume = "12",
number = "6",
pages = "639-653",
doi = "10.2217/fca-2016-0029"
}
Parto, P., Lavie, C. J., Arena, R., Bond, S., Popović, D.,& Ventura, H. O. (2016). Body habitus in heart failure: understanding the mechanisms and clinical significance of the obesity paradox.
Future Cardiology
Future Medicine Ltd, London., 12(6), 639-653.
https://doi.org/10.2217/fca-2016-0029
Parto P, Lavie CJ, Arena R, Bond S, Popović D, Ventura HO. Body habitus in heart failure: understanding the mechanisms and clinical significance of the obesity paradox. Future Cardiology. 2016;12(6):639-653
Parto Parham, Lavie Carl J., Arena Ross, Bond Samantha, Popović Dejana, Ventura Hector O., "Body habitus in heart failure: understanding the mechanisms and clinical significance of the obesity paradox" Future Cardiology, 12, no. 6 (2016):639-653,
https://doi.org/10.2217/fca-2016-0029 .
