Приказ основних података о документу
Cytotoxic and Antimicrobial Activities of Cantharellus cibarius Fr. (Cantarellaceae)
dc.creator | Kolundžić, Marina | |
dc.creator | Stanojković, Tatjana | |
dc.creator | Radović, Jelena | |
dc.creator | Tačić, Ana | |
dc.creator | Dodevska, Margarita | |
dc.creator | Milenković, Marina | |
dc.creator | Sisto, Francesca | |
dc.creator | Masia, Carla | |
dc.creator | Farronato, Giampietro | |
dc.creator | Nikolić, Vesna D. | |
dc.creator | Kundaković, Tatjana | |
dc.date.accessioned | 2019-09-02T11:57:27Z | |
dc.date.available | 2019-09-02T11:57:27Z | |
dc.date.issued | 2017 | |
dc.identifier.issn | 1096-620X | |
dc.identifier.uri | https://farfar.pharmacy.bg.ac.rs/handle/123456789/2798 | |
dc.description.abstract | Antibacterial and cytotoxic activities of cyclohexane, dichloromethane, methanol, and aqueous extracts of Cantharellus cibarius were tested. Broth microdilution assay was performed against 10 bacterial strains (Staphylococcus aureus, S. epidermidis, Micrococcus luteus, Bacillus subtilis, Enterococcus feacalis, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella abony), with emphasis on Helicobacter pylori. Methanol extract was the most active against H. pylori strains with minimal inhibitory concentration values between 4 and 32 mu g/mL. All extracts were active against antibiotic resistant H. pylori. Methanol and aqueous extracts had no cytotoxicity against tested cell lines, whereas cyclohexane and dichloromethane extracts were active against HeLa and N87 cells, but also against healthy MRC-5 cells (IC50 39.26 +/- 1.24-134.79 +/- 0.01 mu g/mL). The tested aqueous extracts have shown 68% of angiotensin-converting enzyme inhibitory activity in doses of 1.25 mg/mL. Chemical analysis has shown the presence of linoleic, cis-vaccenic, and oleic acids, sterols, beta-glucans, and polyphenolic compounds. | en |
dc.publisher | Mary Ann Liebert, Inc, New Rochelle | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173021/RS// | |
dc.rights | restrictedAccess | |
dc.source | Journal of Medicinal Food | |
dc.subject | antibacterial activity | en |
dc.subject | ACE inhibitory activity | en |
dc.subject | beta-glucan | en |
dc.subject | Cantharellus cibarius | en |
dc.subject | cytotoxicity | en |
dc.title | Cytotoxic and Antimicrobial Activities of Cantharellus cibarius Fr. (Cantarellaceae) | en |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Фарронато, Гиампиетро; Миленковић, Марина; Радовић, Јелена; Николић, Весна Д.; Станојковић, Татјана; Тачић, Aна; Колунджић, Марија; Систо, Францесца; Додевска, Маргарита; Кундаковић, Татјана; Масиа, Царла; | |
dc.citation.volume | 20 | |
dc.citation.issue | 8 | |
dc.citation.spage | 790 | |
dc.citation.epage | 796 | |
dc.citation.other | 20(8): 790-796 | |
dc.citation.rank | M22 | |
dc.identifier.wos | 000407429600009 | |
dc.identifier.doi | 10.1089/jmf.2016.0176 | |
dc.identifier.pmid | 28613963 | |
dc.identifier.scopus | 2-s2.0-85027382116 | |
dc.type.version | publishedVersion |