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dc.creatorKolundžić, Marina
dc.creatorStanojković, Tatjana
dc.creatorRadović, Jelena
dc.creatorTačić, Ana
dc.creatorDodevska, Margarita
dc.creatorMilenković, Marina
dc.creatorSisto, Francesca
dc.creatorMasia, Carla
dc.creatorFarronato, Giampietro
dc.creatorNikolić, Vesna D.
dc.creatorKundaković, Tatjana
dc.date.accessioned2019-09-02T11:57:27Z
dc.date.available2019-09-02T11:57:27Z
dc.date.issued2017
dc.identifier.issn1096-620X
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/2798
dc.description.abstractAntibacterial and cytotoxic activities of cyclohexane, dichloromethane, methanol, and aqueous extracts of Cantharellus cibarius were tested. Broth microdilution assay was performed against 10 bacterial strains (Staphylococcus aureus, S. epidermidis, Micrococcus luteus, Bacillus subtilis, Enterococcus feacalis, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella abony), with emphasis on Helicobacter pylori. Methanol extract was the most active against H. pylori strains with minimal inhibitory concentration values between 4 and 32 mu g/mL. All extracts were active against antibiotic resistant H. pylori. Methanol and aqueous extracts had no cytotoxicity against tested cell lines, whereas cyclohexane and dichloromethane extracts were active against HeLa and N87 cells, but also against healthy MRC-5 cells (IC50 39.26 +/- 1.24-134.79 +/- 0.01 mu g/mL). The tested aqueous extracts have shown 68% of angiotensin-converting enzyme inhibitory activity in doses of 1.25 mg/mL. Chemical analysis has shown the presence of linoleic, cis-vaccenic, and oleic acids, sterols, beta-glucans, and polyphenolic compounds.en
dc.publisherMary Ann Liebert, Inc, New Rochelle
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173021/RS//
dc.rightsrestrictedAccess
dc.sourceJournal of Medicinal Food
dc.subjectantibacterial activityen
dc.subjectACE inhibitory activityen
dc.subjectbeta-glucanen
dc.subjectCantharellus cibariusen
dc.subjectcytotoxicityen
dc.titleCytotoxic and Antimicrobial Activities of Cantharellus cibarius Fr. (Cantarellaceae)en
dc.typearticle
dc.rights.licenseARR
dcterms.abstractФарронато, Гиампиетро; Миленковић, Марина; Радовић, Јелена; Николић, Весна Д.; Станојковић, Татјана; Тачић, Aна; Колунджић, Марија; Систо, Францесца; Додевска, Маргарита; Кундаковић, Татјана; Масиа, Царла;
dc.citation.volume20
dc.citation.issue8
dc.citation.spage790
dc.citation.epage796
dc.citation.other20(8): 790-796
dc.citation.rankM22
dc.identifier.wos000407429600009
dc.identifier.doi10.1089/jmf.2016.0176
dc.identifier.pmid28613963
dc.identifier.scopus2-s2.0-85027382116
dc.identifier.rcubconv_3914
dc.type.versionpublishedVersion


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