Effect of dietary manganese supplementation on Mn, Fe, Cu, Zn, Mg, and Ca contents in rat's tissues

Abstract

The aim of this paper was determination of Mn, Fe, Cu, Zn, Mg, and Ca concentrations in different organs of rats supplemented with manganese-proteinate for 43 days. Inorganic forms are usually used as dietary supplements giving free metal ions in intestine for absorption. Different dietary and metabolic factors influence metal ions' absorption and transport. Over the past ten years interest in using minerals bounded to protein ligands has increased because of numerous supposed advantages of organic metal forms. Long-termed intake of moderate doses of supplemental manganese-proteinate increased Mn concentrations in kidney, muscle and skin, but not in liver. At the same time supplementation with Mn significantly influenced levels of Zn and Mg in kidney, Ca in skin and lowered Fe in skin.