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Uporedni prikaz antimikrobne aktivnosti srodnih Co(II)/Cu(II) kompleksa

dc.creatorTanasković, Slađana
dc.creatorAntonijević-Nikolić, Mirjana
dc.creatorDražić, Branka
dc.date.accessioned2019-09-02T11:58:18Z
dc.date.available2019-09-02T11:58:18Z
dc.date.issued2017
dc.identifier.issn0354-6160
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/2834
dc.description.abstractThe aim of this paper is to compare the efficiency of some analogue of Co (II) and Cu (II) complexes to bacteria pathogenic to humans, which can contaminate vegetables and fruit at any stage of its production. The complexes of Cu(II) and Co(II) with N, N’, N’’, N’’’ - tetrakis (2-pyridylmethyl) -1,4,8,11-tetraazacyclotetradecane (tpmc) and various additional ligands were tested against Gram (+) and Gram (-) bacteria and some strains of fungi. As a control group the free salts of Co(II) and Cu(II) which were used as starting substances in the synthesis, as well as ligands and solvents were tested. The minimum inhibition concentrations suppressing the visible growth of bacteria (MIC) were also screened. Investigated complexes showed a moderate activity against strains of bacteria. Complexes of Co(II) generally showed higher activity then Cu(II) analogues. Under the same conditions and the same concentrations, the control group showed no activity. No compound showed antifungal activity.en
dc.description.abstractCilj ovog rada je poređenje efikasnosti nekih analognih kompleksa Co(II) i Cu(II) na bakterijske vrste patogene za čoveka koje mogu kontaminirati povrće i voće u bilo kojoj fazi njegove proizvodnje. Kompleksi Cu (II) i Co (II) sa N, N’, N’’, N’’’ - tetrakis (2-piridilmetil) -1,4,8,11-tetraazaciklotetradekanom (tpmc) i različitim dodatnim ligandima su testirani na Gram (+) i Gram (-) bakterije i neke sojeve gljiva. Kao kontrolna grupa su testirane i proste soli Co(II) i Cu(II) koje su korišćene kao polazne supstance u sintezi kao i ligandi i rastvarači. Određene su minimalne inhibitorne koncentracije (MIC) koje sprečavaju rast mikroorganizama. Ispitivani kompleksi pokazuju umerenu aktivnost prema sojevima bakterija. Kompleksi Co(II) su pokazali generalno već u aktivnost u odnosu na Cu (II) analoge. Pod istim uslovima i u primenjenim istim koncentracijama kontrolne grupe nisu pokazale aktivnost. Nijedno jedinjenje nije ispoljilo antigljivično dejstvo.sr
dc.publisherUniverzitet u Novom Sadu - Poljoprivredni fakultet - Departman za zaštitu bilja i životne sredine "dr Pavla Vukasovića", Novi Sad
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172014/RS//
dc.rightsopenAccess
dc.sourceBiljni lekar
dc.subjectcomplexesen
dc.subjectCo(II)en
dc.subjectCu(II)en
dc.subjectantimicrobial activityen
dc.subjectkompleksisr
dc.subjectCo(II)sr
dc.subjectCu(II)sr
dc.subjectantimikrobna aktivnostsr
dc.titleComparison of the antimicrobial activity of related Co(II)/Cu(II) complexesen
dc.titleUporedni prikaz antimikrobne aktivnosti srodnih Co(II)/Cu(II) kompleksasr
dc.typearticle
dc.rights.licenseARR
dcterms.abstractТанасковић, Слађана; Aнтонијевић-Николић, Мирјана; Дражић, Бранка; Упоредни приказ антимикробне активности сродних Цо(ИИ)/Цу(ИИ) комплекса; Упоредни приказ антимикробне активности сродних Цо(ИИ)/Цу(ИИ) комплекса;
dc.citation.volume45
dc.citation.issue3
dc.citation.spage321
dc.citation.epage325
dc.citation.other45(3): 321-325
dc.citation.rankM52
dc.identifier.fulltexthttp://farfar.pharmacy.bg.ac.rs//bitstream/id/1466/2832.pdf
dc.identifier.rcubconv_894
dc.type.versionpublishedVersion


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