Synthesis of substituted allyl acetates from heterocyclic dienes by a Pd-promoted arylation-acetoxylation cascade
Апстракт
Pd-catalysed arylation-acetoxylation cascade, a previously reported methodology, was applied in the functionalisation of unsymmetrical dienes. Both explored classes of compounds, isoquinoline and ss-carboline-derived dienes, afforded single regioisomers. Although further improvements of the process are necessary, primarily due to lower yields, the described functionalisation of the studied compounds might be useful in the synthesis of emetine and related naturally occurring compounds.
Извор:
Journal of the Serbian Chemical Society, 2017, 82, 12, 1335-1341Издавач:
- Srpsko hemijsko društvo, Beograd
Финансирање / пројекти:
- Компјутерско дизајнирање, синтеза и биолошка евалуација нових хетероцикличних једињења као селективних инхибитора туморогенезе (RS-MESTD-Basic Research (BR or ON)-172009)
DOI: 10.2298/JSC170317046S
ISSN: 0352-5139
WoS: 000419391700001
Scopus: 2-s2.0-85040055713
Институција/група
PharmacyTY - JOUR AU - Simić, Milena AU - Petković, Miloš AU - Jovanović, Predrag AU - Tasić, Gordana AU - Savić, Vladimir PY - 2017 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2842 AB - Pd-catalysed arylation-acetoxylation cascade, a previously reported methodology, was applied in the functionalisation of unsymmetrical dienes. Both explored classes of compounds, isoquinoline and ss-carboline-derived dienes, afforded single regioisomers. Although further improvements of the process are necessary, primarily due to lower yields, the described functionalisation of the studied compounds might be useful in the synthesis of emetine and related naturally occurring compounds. PB - Srpsko hemijsko društvo, Beograd T2 - Journal of the Serbian Chemical Society T1 - Synthesis of substituted allyl acetates from heterocyclic dienes by a Pd-promoted arylation-acetoxylation cascade VL - 82 IS - 12 SP - 1335 EP - 1341 DO - 10.2298/JSC170317046S ER -
@article{ author = "Simić, Milena and Petković, Miloš and Jovanović, Predrag and Tasić, Gordana and Savić, Vladimir", year = "2017", abstract = "Pd-catalysed arylation-acetoxylation cascade, a previously reported methodology, was applied in the functionalisation of unsymmetrical dienes. Both explored classes of compounds, isoquinoline and ss-carboline-derived dienes, afforded single regioisomers. Although further improvements of the process are necessary, primarily due to lower yields, the described functionalisation of the studied compounds might be useful in the synthesis of emetine and related naturally occurring compounds.", publisher = "Srpsko hemijsko društvo, Beograd", journal = "Journal of the Serbian Chemical Society", title = "Synthesis of substituted allyl acetates from heterocyclic dienes by a Pd-promoted arylation-acetoxylation cascade", volume = "82", number = "12", pages = "1335-1341", doi = "10.2298/JSC170317046S" }
Simić, M., Petković, M., Jovanović, P., Tasić, G.,& Savić, V.. (2017). Synthesis of substituted allyl acetates from heterocyclic dienes by a Pd-promoted arylation-acetoxylation cascade. in Journal of the Serbian Chemical Society Srpsko hemijsko društvo, Beograd., 82(12), 1335-1341. https://doi.org/10.2298/JSC170317046S
Simić M, Petković M, Jovanović P, Tasić G, Savić V. Synthesis of substituted allyl acetates from heterocyclic dienes by a Pd-promoted arylation-acetoxylation cascade. in Journal of the Serbian Chemical Society. 2017;82(12):1335-1341. doi:10.2298/JSC170317046S .
Simić, Milena, Petković, Miloš, Jovanović, Predrag, Tasić, Gordana, Savić, Vladimir, "Synthesis of substituted allyl acetates from heterocyclic dienes by a Pd-promoted arylation-acetoxylation cascade" in Journal of the Serbian Chemical Society, 82, no. 12 (2017):1335-1341, https://doi.org/10.2298/JSC170317046S . .