Show simple item record

dc.creatorPetrović, Silvana
dc.creatorDrobac, Milica
dc.creatorUšjak, Ljuboš
dc.creatorFilipović, Vladimir
dc.creatorMilenković, Marina
dc.creatorNiketić, Marjan
dc.date.accessioned2019-09-02T11:58:34Z
dc.date.available2019-09-02T11:58:34Z
dc.date.issued2017
dc.identifier.issn0926-6690
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/2847
dc.description.abstractThe plants of the genus Armoracia P. Gaertn., B. Mey. & Scherb. (Brassicaceae) contain glucosinolates, which volatile hydrolysis products are known for their antimicrobial activity. In this work, the composition and antimicrobial activity of the root volatiles of wild-growing Armoracia macrocarpa (Waldst. & Kit.) Kit. ex Baumg., obtained by hydrodistillation, were analysed for the first time. These results were compared with those of widely used horseradish, A. rusticana P. Gaertn., B. Mey. & Scherb. Additionally, the possibility of the propagation of A. macrocarpa from the roots, and impact of its cultivation on the composition and antimicrobial activity of the root volatiles were investigated. The GC-FID and GC-MS analysis revealed that all A. macrocarpa root volatile fractions were dominated by berteroin (55.0-59.0%) and lesquerellin (34.1-36.4%), and were significantly different from horseradish root volatile fraction. In microdilution method, A. macrocarpa volatile fractions exhibited weak/no antibacterial activity, while their effect against standard strain (MICs = 4.8-9.3 µg/mL) and clinical isolates (MICs = 25-119 µg/mL) of Candida albicans was significant. Horseradish volatiles exhibited better antibacterial and slightly weaker anticandidal activity. Armoracia macrocarpa represents a new source of raw materials with potential use in pharmaceutical and food industries, as well as in cookery. Preliminary results indicated the possibility of its cultivation, which is required for its preservation and sustainable usage.en
dc.publisherElsevier Science BV, Amsterdam
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173021/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/46006/RS//
dc.rightsrestrictedAccess
dc.sourceIndustrial Crops and Products
dc.subjectArmoracia macrocarpaen
dc.subjectArmoracia rusticanaen
dc.subjectRoot volatilesen
dc.subjectGC-FID and GC MSen
dc.subjectAntibacterial activityen
dc.subjectAnticandidal activityen
dc.titleVolatiles of roots of wild-growing and cultivated Armoracia macrocarpa and their antimicrobial activity, in comparison to horseradish, A. rusticanaen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractФилиповић, Владимир; Ушјак, Љубош; Дробац, Милица; Миленковић, Марина; Никетић, Марјан; Петровић, Силвана;
dc.citation.volume109
dc.citation.spage398
dc.citation.epage403
dc.citation.other109: 398-403
dc.citation.rankaM21
dc.identifier.wos000413880300049
dc.identifier.doi10.1016/j.indcrop.2017.08.056
dc.identifier.scopus2-s2.0-85028694667
dc.identifier.rcubconv_3978
dc.type.versionpublishedVersion


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record