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Obesity, body composition and cardiorespiratory fitness in heart failure with preserved ejection fraction

Authorized Users Only
2017
Authors
Carbone, Salvatore
Popović, Dejana
Lavie, Carl J.
Arena, Ross
Article (Published version)
Metadata
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Abstract
Obesity is defined as an excess body fat that impairs health and is associated with increased risk of heart failure (HF), particularly HF with preserved ejection fraction (HFpEF), evolving into a 'HFpEF obesity phenotype'. The interplay between obesity and cardiorespiratory fitness, primary clinical parameters in HF, requires further exploration. The contribution of body composition compartments in the development and progress of HF has been the object of numerous studies. Here we focus on how fat mass and lean tissues affect cardiorespiratory fitness, with emphasis on their effects on peak oxygen consumption. Moreover, while several studies have focused on characterization of body composition compartments, here we describe also recent findings related to abnormal and/or dysfunctional lean mass, especially in HFpEF.
Keywords:
body composition / cardiorespiratory fitness / fat mass / heart failure with preserved ejection fraction / lean mass / skeletal muscle mass
Source:
Future Cardiology, 2017, 13, 5, 451-463
Publisher:
  • Future Medicine Ltd, London
Funding / projects:
  • Mentored Clinical & Population Research Award from the American Heart Association - 16MCPRP31100003

DOI: 10.2217/fca-2017-0023

ISSN: 1479-6678

WoS: 000418475500007

Scopus: 2-s2.0-85029663418
[ Google Scholar ]
32
21
URI
https://farfar.pharmacy.bg.ac.rs/handle/123456789/2854
Collections
  • Radovi istraživača / Researchers’ publications
Institution/Community
Pharmacy
TY  - JOUR
AU  - Carbone, Salvatore
AU  - Popović, Dejana
AU  - Lavie, Carl J.
AU  - Arena, Ross
PY  - 2017
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2854
AB  - Obesity is defined as an excess body fat that impairs health and is associated with increased risk of heart failure (HF), particularly HF with preserved ejection fraction (HFpEF), evolving into a 'HFpEF obesity phenotype'. The interplay between obesity and cardiorespiratory fitness, primary clinical parameters in HF, requires further exploration. The contribution of body composition compartments in the development and progress of HF has been the object of numerous studies. Here we focus on how fat mass and lean tissues affect cardiorespiratory fitness, with emphasis on their effects on peak oxygen consumption. Moreover, while several studies have focused on characterization of body composition compartments, here we describe also recent findings related to abnormal and/or dysfunctional lean mass, especially in HFpEF.
PB  - Future Medicine Ltd, London
T2  - Future Cardiology
T1  - Obesity, body composition and cardiorespiratory fitness in heart failure with preserved ejection fraction
VL  - 13
IS  - 5
SP  - 451
EP  - 463
DO  - 10.2217/fca-2017-0023
ER  - 
@article{
author = "Carbone, Salvatore and Popović, Dejana and Lavie, Carl J. and Arena, Ross",
year = "2017",
abstract = "Obesity is defined as an excess body fat that impairs health and is associated with increased risk of heart failure (HF), particularly HF with preserved ejection fraction (HFpEF), evolving into a 'HFpEF obesity phenotype'. The interplay between obesity and cardiorespiratory fitness, primary clinical parameters in HF, requires further exploration. The contribution of body composition compartments in the development and progress of HF has been the object of numerous studies. Here we focus on how fat mass and lean tissues affect cardiorespiratory fitness, with emphasis on their effects on peak oxygen consumption. Moreover, while several studies have focused on characterization of body composition compartments, here we describe also recent findings related to abnormal and/or dysfunctional lean mass, especially in HFpEF.",
publisher = "Future Medicine Ltd, London",
journal = "Future Cardiology",
title = "Obesity, body composition and cardiorespiratory fitness in heart failure with preserved ejection fraction",
volume = "13",
number = "5",
pages = "451-463",
doi = "10.2217/fca-2017-0023"
}
Carbone, S., Popović, D., Lavie, C. J.,& Arena, R.. (2017). Obesity, body composition and cardiorespiratory fitness in heart failure with preserved ejection fraction. in Future Cardiology
Future Medicine Ltd, London., 13(5), 451-463.
https://doi.org/10.2217/fca-2017-0023
Carbone S, Popović D, Lavie CJ, Arena R. Obesity, body composition and cardiorespiratory fitness in heart failure with preserved ejection fraction. in Future Cardiology. 2017;13(5):451-463.
doi:10.2217/fca-2017-0023 .
Carbone, Salvatore, Popović, Dejana, Lavie, Carl J., Arena, Ross, "Obesity, body composition and cardiorespiratory fitness in heart failure with preserved ejection fraction" in Future Cardiology, 13, no. 5 (2017):451-463,
https://doi.org/10.2217/fca-2017-0023 . .

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