Environmental exposure to organophosphorus nerve agents
Samo za registrovane korisnike
2017
Autori
Vučinić, SlavicaAntonijević, Biljana
Tsatsakis, Aristidis
Vassilopoulou, Loukia
Docea, Anca Oana
Nosyrev, Alexander E.
Izotov, Boris N.
Thiermann, Horst
Drakoulis, Nikolaos
Brkić, Dragica
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Exposure to organophosphorus nerve agents, the most deadly chemical warfare agents, is possible in a variety of situations, such as destruction of chemical warfare agents, terrorist attacks, armed conflicts or accidents in research laboratories and storage facilities. Hundreds of thousands of tons of chemical munitions were disposed of at the sea in the post World War II period, with European, Russian, Japanese and US coasts being the most affected. Sulfur mustard, Lewisite and nerve agents appear to be the most frequently chemical warfare agents disposed of at the sea. Addressing the overall environmental risk, it has been one of the priorities of the world community since that time. Aside from confirming exposure to nerve agents in the alleged use for forensic purposes, the detection and identification of biological markers of exposure are also needed for the diagnosis and treatment of poisoning, in addition to occupational health monitoring for specific profiles of workers. When est...imating detrimental effects of acute or potential chronic sub-lethal doses of organophosphorus nerve agents, released accidentally or intentionally into the environment, it is necessary to understand the wide spectra of physical, chemical and toxicological properties of these agents, and predict their ultimate fate in environmental systems.
Ključne reči:
Chemical warfare agents / Biological markers / Risk assessment / Environmental persistence / Field management and triageIzvor:
Environmental Toxicology and Pharmacology, 2017, 56, 163-171Izdavač:
- Elsevier Science BV, Amsterdam
DOI: 10.1016/j.etap.2017.09.004
ISSN: 1382-6689
PubMed: 28942081
WoS: 000418222300023
Scopus: 2-s2.0-85029693181
Institucija/grupa
PharmacyTY - JOUR AU - Vučinić, Slavica AU - Antonijević, Biljana AU - Tsatsakis, Aristidis AU - Vassilopoulou, Loukia AU - Docea, Anca Oana AU - Nosyrev, Alexander E. AU - Izotov, Boris N. AU - Thiermann, Horst AU - Drakoulis, Nikolaos AU - Brkić, Dragica PY - 2017 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2856 AB - Exposure to organophosphorus nerve agents, the most deadly chemical warfare agents, is possible in a variety of situations, such as destruction of chemical warfare agents, terrorist attacks, armed conflicts or accidents in research laboratories and storage facilities. Hundreds of thousands of tons of chemical munitions were disposed of at the sea in the post World War II period, with European, Russian, Japanese and US coasts being the most affected. Sulfur mustard, Lewisite and nerve agents appear to be the most frequently chemical warfare agents disposed of at the sea. Addressing the overall environmental risk, it has been one of the priorities of the world community since that time. Aside from confirming exposure to nerve agents in the alleged use for forensic purposes, the detection and identification of biological markers of exposure are also needed for the diagnosis and treatment of poisoning, in addition to occupational health monitoring for specific profiles of workers. When estimating detrimental effects of acute or potential chronic sub-lethal doses of organophosphorus nerve agents, released accidentally or intentionally into the environment, it is necessary to understand the wide spectra of physical, chemical and toxicological properties of these agents, and predict their ultimate fate in environmental systems. PB - Elsevier Science BV, Amsterdam T2 - Environmental Toxicology and Pharmacology T1 - Environmental exposure to organophosphorus nerve agents VL - 56 SP - 163 EP - 171 DO - 10.1016/j.etap.2017.09.004 ER -
@article{ author = "Vučinić, Slavica and Antonijević, Biljana and Tsatsakis, Aristidis and Vassilopoulou, Loukia and Docea, Anca Oana and Nosyrev, Alexander E. and Izotov, Boris N. and Thiermann, Horst and Drakoulis, Nikolaos and Brkić, Dragica", year = "2017", abstract = "Exposure to organophosphorus nerve agents, the most deadly chemical warfare agents, is possible in a variety of situations, such as destruction of chemical warfare agents, terrorist attacks, armed conflicts or accidents in research laboratories and storage facilities. Hundreds of thousands of tons of chemical munitions were disposed of at the sea in the post World War II period, with European, Russian, Japanese and US coasts being the most affected. Sulfur mustard, Lewisite and nerve agents appear to be the most frequently chemical warfare agents disposed of at the sea. Addressing the overall environmental risk, it has been one of the priorities of the world community since that time. Aside from confirming exposure to nerve agents in the alleged use for forensic purposes, the detection and identification of biological markers of exposure are also needed for the diagnosis and treatment of poisoning, in addition to occupational health monitoring for specific profiles of workers. When estimating detrimental effects of acute or potential chronic sub-lethal doses of organophosphorus nerve agents, released accidentally or intentionally into the environment, it is necessary to understand the wide spectra of physical, chemical and toxicological properties of these agents, and predict their ultimate fate in environmental systems.", publisher = "Elsevier Science BV, Amsterdam", journal = "Environmental Toxicology and Pharmacology", title = "Environmental exposure to organophosphorus nerve agents", volume = "56", pages = "163-171", doi = "10.1016/j.etap.2017.09.004" }
Vučinić, S., Antonijević, B., Tsatsakis, A., Vassilopoulou, L., Docea, A. O., Nosyrev, A. E., Izotov, B. N., Thiermann, H., Drakoulis, N.,& Brkić, D.. (2017). Environmental exposure to organophosphorus nerve agents. in Environmental Toxicology and Pharmacology Elsevier Science BV, Amsterdam., 56, 163-171. https://doi.org/10.1016/j.etap.2017.09.004
Vučinić S, Antonijević B, Tsatsakis A, Vassilopoulou L, Docea AO, Nosyrev AE, Izotov BN, Thiermann H, Drakoulis N, Brkić D. Environmental exposure to organophosphorus nerve agents. in Environmental Toxicology and Pharmacology. 2017;56:163-171. doi:10.1016/j.etap.2017.09.004 .
Vučinić, Slavica, Antonijević, Biljana, Tsatsakis, Aristidis, Vassilopoulou, Loukia, Docea, Anca Oana, Nosyrev, Alexander E., Izotov, Boris N., Thiermann, Horst, Drakoulis, Nikolaos, Brkić, Dragica, "Environmental exposure to organophosphorus nerve agents" in Environmental Toxicology and Pharmacology, 56 (2017):163-171, https://doi.org/10.1016/j.etap.2017.09.004 . .