FarFaR - Pharmacy Repository
University of Belgrade, Faculty of Pharmacy
    • English
    • Српски
    • Српски (Serbia)
  • English 
    • English
    • Serbian (Cyrillic)
    • Serbian (Latin)
  • Login
View Item 
  •   FarFaR
  • Pharmacy
  • Radovi istraživača / Researchers’ publications
  • View Item
  •   FarFaR
  • Pharmacy
  • Radovi istraživača / Researchers’ publications
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Comparative Analysis of Phenolic Compounds in Seven Hypericum Species and Their Antioxidant Properties

Thumbnail
2017
2857.pdf (325.1Kb)
Authors
Zdunić, Gordana
Gođevac, Dejan
Šavikin, Katarina
Petrović, Silvana
Article (Published version)
Metadata
Show full item record
Abstract
A comparative analysis of the phenolic compounds in the 70% EtOH extracts of Hypericum acutum, H. androsaemum, H. barbatum, H hirsutum, H maculatum, and H richeri has been carried out using high-performance liquid chromatography coupled with photodiode array UV detection and high resolution TOF mass spectrometry. Quercetin, astilbin, I3,II8-biapigenin, orientin, 2"-O-acetylorientin, three phenolcarboxylic acids, and eight flavonols 3-O-glycosides were identified in the extracts on the basis of their on-line UV spectra, accurate mass spectral data, and in comparison of retention times with those from the standards. Fingerprint analysis of the extracts revealed significant differences in the qualitative and quantitative chemical composition of the studied species. Antioxidant assays with various reaction mechanisms were used including ferric reducing antioxidant power (FRAP) assay, DPPH, ABTS, superoxide anion radical scavenging capacity and inhibition of liposome peroxidation induced by... Fe2+. The most potent were extracts of H acutum and H maculatum indicating this Hypericum species interesting for further research aimed as a potentially new source of biologically active compounds.

Keywords:
Hypericum species / Chemical analysis / LC/MS / HPLC/DAD / Antioxidant activity
Source:
Natural Product Communications, 2017, 12, 11, 1805-1811
Publisher:
  • Sage Publications Inc, Thousand Oaks

ISSN: 1934-578X

WoS: 000417552000039

Scopus: 2-s2.0-85035243200
[ Google Scholar ]
21
9
Handle
https://hdl.handle.net/21.15107/rcub_farfar_2859
URI
https://farfar.pharmacy.bg.ac.rs/handle/123456789/2859
Collections
  • Radovi istraživača / Researchers’ publications
Institution/Community
Pharmacy
TY  - JOUR
AU  - Zdunić, Gordana
AU  - Gođevac, Dejan
AU  - Šavikin, Katarina
AU  - Petrović, Silvana
PY  - 2017
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2859
AB  - A comparative analysis of the phenolic compounds in the 70% EtOH extracts of Hypericum acutum, H. androsaemum, H. barbatum, H hirsutum, H maculatum, and H richeri has been carried out using high-performance liquid chromatography coupled with photodiode array UV detection and high resolution TOF mass spectrometry. Quercetin, astilbin, I3,II8-biapigenin, orientin, 2"-O-acetylorientin, three phenolcarboxylic acids, and eight flavonols 3-O-glycosides were identified in the extracts on the basis of their on-line UV spectra, accurate mass spectral data, and in comparison of retention times with those from the standards. Fingerprint analysis of the extracts revealed significant differences in the qualitative and quantitative chemical composition of the studied species. Antioxidant assays with various reaction mechanisms were used including ferric reducing antioxidant power (FRAP) assay, DPPH, ABTS, superoxide anion radical scavenging capacity and inhibition of liposome peroxidation induced by Fe2+. The most potent were extracts of H acutum and H maculatum indicating this Hypericum species interesting for further research aimed as a potentially new source of biologically active compounds.
PB  - Sage Publications Inc, Thousand Oaks
T2  - Natural Product Communications
T1  - Comparative Analysis of Phenolic Compounds in Seven Hypericum Species and Their Antioxidant Properties
VL  - 12
IS  - 11
SP  - 1805
EP  - 1811
UR  - https://hdl.handle.net/21.15107/rcub_farfar_2859
ER  - 
@article{
author = "Zdunić, Gordana and Gođevac, Dejan and Šavikin, Katarina and Petrović, Silvana",
year = "2017",
abstract = "A comparative analysis of the phenolic compounds in the 70% EtOH extracts of Hypericum acutum, H. androsaemum, H. barbatum, H hirsutum, H maculatum, and H richeri has been carried out using high-performance liquid chromatography coupled with photodiode array UV detection and high resolution TOF mass spectrometry. Quercetin, astilbin, I3,II8-biapigenin, orientin, 2"-O-acetylorientin, three phenolcarboxylic acids, and eight flavonols 3-O-glycosides were identified in the extracts on the basis of their on-line UV spectra, accurate mass spectral data, and in comparison of retention times with those from the standards. Fingerprint analysis of the extracts revealed significant differences in the qualitative and quantitative chemical composition of the studied species. Antioxidant assays with various reaction mechanisms were used including ferric reducing antioxidant power (FRAP) assay, DPPH, ABTS, superoxide anion radical scavenging capacity and inhibition of liposome peroxidation induced by Fe2+. The most potent were extracts of H acutum and H maculatum indicating this Hypericum species interesting for further research aimed as a potentially new source of biologically active compounds.",
publisher = "Sage Publications Inc, Thousand Oaks",
journal = "Natural Product Communications",
title = "Comparative Analysis of Phenolic Compounds in Seven Hypericum Species and Their Antioxidant Properties",
volume = "12",
number = "11",
pages = "1805-1811",
url = "https://hdl.handle.net/21.15107/rcub_farfar_2859"
}
Zdunić, G., Gođevac, D., Šavikin, K.,& Petrović, S.. (2017). Comparative Analysis of Phenolic Compounds in Seven Hypericum Species and Their Antioxidant Properties. in Natural Product Communications
Sage Publications Inc, Thousand Oaks., 12(11), 1805-1811.
https://hdl.handle.net/21.15107/rcub_farfar_2859
Zdunić G, Gođevac D, Šavikin K, Petrović S. Comparative Analysis of Phenolic Compounds in Seven Hypericum Species and Their Antioxidant Properties. in Natural Product Communications. 2017;12(11):1805-1811.
https://hdl.handle.net/21.15107/rcub_farfar_2859 .
Zdunić, Gordana, Gođevac, Dejan, Šavikin, Katarina, Petrović, Silvana, "Comparative Analysis of Phenolic Compounds in Seven Hypericum Species and Their Antioxidant Properties" in Natural Product Communications, 12, no. 11 (2017):1805-1811,
https://hdl.handle.net/21.15107/rcub_farfar_2859 .

DSpace software copyright © 2002-2015  DuraSpace
About FarFaR - Pharmacy Repository | Send Feedback

OpenAIRERCUB
 

 

All of DSpaceCommunitiesAuthorsTitlesSubjectsThis institutionAuthorsTitlesSubjects

Statistics

View Usage Statistics

DSpace software copyright © 2002-2015  DuraSpace
About FarFaR - Pharmacy Repository | Send Feedback

OpenAIRERCUB