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Anti α-glucosidase, antitumour, antioxidative, antimicrobial activity, nutritive and health protective potential of some seaweeds from the Adriatic coast of Montenegro
The aim of the present study was to reveal the potential biological activities of the dichlorometane: methanol (1:1) dry extract (DME) and the nutritional value of selected seaweeds: Cymodocea nodosa, Halimeda tuna, Cystoseira barbata and Codium bursa, collected from the Adriatic coast, Montenegro. We assessed the chemical composition and several biological activities such as: anti-a-glucosidase, antitumour, antimicrobial and antioxidative activity. H. tuna had the best cytotoxic activity against human colon carcinoma cell line, LS174 (IC50 = 17.92 +/- 1.54 mu g/mL). C. nodosa demonstrated strong cytotoxicity against human adenocarcinoma cell line, HeLa (IC50 = 13.28 +/- 0.39 mu g/mL) and human chronic myelogenous leukaemia cell line, K562 (IC50 = 19.64 +/- 1.55 mu g/mL). C. barbata had the best anti a-glucosidase (IC50 = 9.98 +/- 3.34 mu g/mL) and antimicrobial activity (minimal inhibitory concentration of 100 mu g/mL) for Staphylococcus aureus and Bacillus subtilis. C. bursa showed t...he highest nutritional value (490.4 kcal).
TY - JOUR
AU - Milović, Sanja
AU - Kundaković, Tatjana
AU - Macić, Vesna
AU - Antić-Stanković, Jelena
AU - Grozdanić, Nada
AU - Đuričić, Ivana
AU - Stanković, Ivan
AU - Stanojković, Tatjana
PY - 2017
UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2866
AB - The aim of the present study was to reveal the potential biological activities of the dichlorometane: methanol (1:1) dry extract (DME) and the nutritional value of selected seaweeds: Cymodocea nodosa, Halimeda tuna, Cystoseira barbata and Codium bursa, collected from the Adriatic coast, Montenegro. We assessed the chemical composition and several biological activities such as: anti-a-glucosidase, antitumour, antimicrobial and antioxidative activity. H. tuna had the best cytotoxic activity against human colon carcinoma cell line, LS174 (IC50 = 17.92 +/- 1.54 mu g/mL). C. nodosa demonstrated strong cytotoxicity against human adenocarcinoma cell line, HeLa (IC50 = 13.28 +/- 0.39 mu g/mL) and human chronic myelogenous leukaemia cell line, K562 (IC50 = 19.64 +/- 1.55 mu g/mL). C. barbata had the best anti a-glucosidase (IC50 = 9.98 +/- 3.34 mu g/mL) and antimicrobial activity (minimal inhibitory concentration of 100 mu g/mL) for Staphylococcus aureus and Bacillus subtilis. C. bursa showed the highest nutritional value (490.4 kcal).
PB - Soc Stinte Farmaceutice Romania, Bucuresti
T2 - Farmacia
T1 - Anti α-glucosidase, antitumour, antioxidative, antimicrobial activity, nutritive and health protective potential of some seaweeds from the Adriatic coast of Montenegro
VL - 65
IS - 5
SP - 731
EP - 740
UR - https://hdl.handle.net/21.15107/rcub_farfar_2866
ER -
@article{
author = "Milović, Sanja and Kundaković, Tatjana and Macić, Vesna and Antić-Stanković, Jelena and Grozdanić, Nada and Đuričić, Ivana and Stanković, Ivan and Stanojković, Tatjana",
year = "2017",
abstract = "The aim of the present study was to reveal the potential biological activities of the dichlorometane: methanol (1:1) dry extract (DME) and the nutritional value of selected seaweeds: Cymodocea nodosa, Halimeda tuna, Cystoseira barbata and Codium bursa, collected from the Adriatic coast, Montenegro. We assessed the chemical composition and several biological activities such as: anti-a-glucosidase, antitumour, antimicrobial and antioxidative activity. H. tuna had the best cytotoxic activity against human colon carcinoma cell line, LS174 (IC50 = 17.92 +/- 1.54 mu g/mL). C. nodosa demonstrated strong cytotoxicity against human adenocarcinoma cell line, HeLa (IC50 = 13.28 +/- 0.39 mu g/mL) and human chronic myelogenous leukaemia cell line, K562 (IC50 = 19.64 +/- 1.55 mu g/mL). C. barbata had the best anti a-glucosidase (IC50 = 9.98 +/- 3.34 mu g/mL) and antimicrobial activity (minimal inhibitory concentration of 100 mu g/mL) for Staphylococcus aureus and Bacillus subtilis. C. bursa showed the highest nutritional value (490.4 kcal).",
publisher = "Soc Stinte Farmaceutice Romania, Bucuresti",
journal = "Farmacia",
title = "Anti α-glucosidase, antitumour, antioxidative, antimicrobial activity, nutritive and health protective potential of some seaweeds from the Adriatic coast of Montenegro",
volume = "65",
number = "5",
pages = "731-740",
url = "https://hdl.handle.net/21.15107/rcub_farfar_2866"
}
Milović, S., Kundaković, T., Macić, V., Antić-Stanković, J., Grozdanić, N., Đuričić, I., Stanković, I.,& Stanojković, T.. (2017). Anti α-glucosidase, antitumour, antioxidative, antimicrobial activity, nutritive and health protective potential of some seaweeds from the Adriatic coast of Montenegro. in Farmacia
Soc Stinte Farmaceutice Romania, Bucuresti., 65(5), 731-740.
https://hdl.handle.net/21.15107/rcub_farfar_2866
Milović S, Kundaković T, Macić V, Antić-Stanković J, Grozdanić N, Đuričić I, Stanković I, Stanojković T. Anti α-glucosidase, antitumour, antioxidative, antimicrobial activity, nutritive and health protective potential of some seaweeds from the Adriatic coast of Montenegro. in Farmacia. 2017;65(5):731-740.
https://hdl.handle.net/21.15107/rcub_farfar_2866 .
Milović, Sanja, Kundaković, Tatjana, Macić, Vesna, Antić-Stanković, Jelena, Grozdanić, Nada, Đuričić, Ivana, Stanković, Ivan, Stanojković, Tatjana, "Anti α-glucosidase, antitumour, antioxidative, antimicrobial activity, nutritive and health protective potential of some seaweeds from the Adriatic coast of Montenegro" in Farmacia, 65, no. 5 (2017):731-740,
https://hdl.handle.net/21.15107/rcub_farfar_2866 .
