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dc.creatorMilović, Sanja
dc.creatorKundaković, Tatjana
dc.creatorMacić, Vesna
dc.creatorAntić-Stanković, Jelena
dc.creatorGrozdanić, Nada
dc.creatorĐuričić, Ivana
dc.creatorStanković, Ivan
dc.creatorStanojković, Tatjana
dc.date.accessioned2019-09-02T11:59:01Z
dc.date.available2019-09-02T11:59:01Z
dc.date.issued2017
dc.identifier.issn0014-8237
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/2866
dc.description.abstractThe aim of the present study was to reveal the potential biological activities of the dichlorometane: methanol (1:1) dry extract (DME) and the nutritional value of selected seaweeds: Cymodocea nodosa, Halimeda tuna, Cystoseira barbata and Codium bursa, collected from the Adriatic coast, Montenegro. We assessed the chemical composition and several biological activities such as: anti-a-glucosidase, antitumour, antimicrobial and antioxidative activity. H. tuna had the best cytotoxic activity against human colon carcinoma cell line, LS174 (IC50 = 17.92 +/- 1.54 mu g/mL). C. nodosa demonstrated strong cytotoxicity against human adenocarcinoma cell line, HeLa (IC50 = 13.28 +/- 0.39 mu g/mL) and human chronic myelogenous leukaemia cell line, K562 (IC50 = 19.64 +/- 1.55 mu g/mL). C. barbata had the best anti a-glucosidase (IC50 = 9.98 +/- 3.34 mu g/mL) and antimicrobial activity (minimal inhibitory concentration of 100 mu g/mL) for Staphylococcus aureus and Bacillus subtilis. C. bursa showed the highest nutritional value (490.4 kcal).en
dc.publisherSoc Stinte Farmaceutice Romania, Bucuresti
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/175011/RS//
dc.relationproject KOTOR - Institute of Marine Biology, Department of Chemistry Biochemistry and Molecular Bi
dc.rightsrestrictedAccess
dc.sourceFarmacia
dc.subjectbiological activitiesen
dc.subjectseaweeden
dc.subjectnutrientsen
dc.subjectanti alpha-glucosidaseen
dc.subjectantitumouren
dc.subjectantimicrobialen
dc.subjectantioxidanten
dc.titleAnti alpha-glucosidase, antitumour, antioxidative, antimicrobial activity, nutritive and health protective potential of some seaweeds from the Adriatic coast of Montenegroen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractМацић, Весна; Ђуричић, Ивана; Грозданић, Нада; Станојковић, Татјана; Станковић, Иван; Aнтић-Станковић, Јелена; Кундаковић, Татјана; Миловић, Сања;
dc.citation.volume65
dc.citation.issue5
dc.citation.spage731
dc.citation.epage740
dc.citation.other65(5): 731-740
dc.citation.rankM23
dc.identifier.wos000413731300013
dc.identifier.scopus2-s2.0-85032356666
dc.identifier.rcubconv_3970
dc.type.versionpublishedVersion


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