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dc.creatorPetrović, Silvana
dc.creatorUšjak, Ljuboš
dc.creatorMilenković, Marina
dc.creatorArsenijević, Jelena
dc.creatorDrobac, Milica
dc.creatorDrndarević, Aneta
dc.creatorNiketić, Marjan
dc.date.accessioned2019-09-02T12:01:26Z
dc.date.available2019-09-02T12:01:26Z
dc.date.issued2017
dc.identifier.issn1756-4646
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/2959
dc.description.abstractIn a search for novel food additives functional food ingredients, chemical composition, and antioxidant and antimicrobial activities of Thymus dacicus Borbas (Lamiaceae) flowering aerial parts dry methanol extract and essential oil were tested for the first time. HPLC analysis of the extract revealed that among dominant polyphenols, rosmarinic acid was the most abundant (71.33 +/- 1.11 mg/g). Monoterpenes geranial (34.4%) and neral (23.9%) prevailed in the oil, analyzed by GC and GC-MS. The extract showed pronounced antioxidant activity, with FRAP value of 5.16 +/- 0.19 mmol Fe2+/g, OH radical SC50 of 18.85 µg/mL (determined by 2-deoxyribose assay) and DPPH radical SC50 of 28.04 µg/mL. Eight out of ten tested microbial strains were susceptible to the oil in microdilution test. Furthermore, for the combination of the oil and vancomycin/gentamicin, synergism was demonstrated against MRSA, Klebsiella pneumoniae and Escherichia coli in checkerboard test. Obtained results encourage further research of this herb as potentially beneficial ingredient in foodstuffs.en
dc.publisherElsevier Science BV, Amsterdam
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173021/RS//
dc.rightsrestrictedAccess
dc.sourceJournal of Functional Foods
dc.titleThymus dacicus as a new source of antioxidant and antimicrobial metabolitesen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractПетровић, Силвана; Дробац, Милица; Ушјак, Љубош; Дрндаревић, Aнета; Миленковић, Марина; Никетић, Марјан; Aрсенијевић, Јелена;
dc.citation.volume28
dc.citation.spage114
dc.citation.epage121
dc.citation.other28: 114-121
dc.citation.rankM21
dc.identifier.wos000392885000014
dc.identifier.doi10.1016/j.jff.2016.11.007
dc.identifier.scopus2-s2.0-84998780318
dc.identifier.rcubconv_3752
dc.type.versionpublishedVersion


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