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Derivative spectrophotometric method for determination of acidity constants of single step acid-base equilibria

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2001
Authors
Popović, Gordana
Pfendt, Lidija
Moskovljević, VM
Article (Published version)
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Abstract
A general derivative spectrophotometric method for determination of acidity constants is developed. The method appears suitable in cases when classical spectrophotometry cannot be employed due to little differences in the absorption spectra of conjugated acid-base pairs. Based on theoretical considerations, seven variants of the method have been established and their validity was checked, determining acidity constants of lorazepam and flurazepam as model compounds.
Source:
Talanta, 2001, 55, 2, 363-370
Publisher:
  • Elsevier Science BV, Amsterdam

DOI: 10.1016/S0039-9140(01)00433-7

ISSN: 0039-9140

PubMed: 18968381

WoS: 000171174600018

Scopus: 2-s2.0-0035974972
[ Google Scholar ]
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6
URI
http://farfar.pharmacy.bg.ac.rs/handle/123456789/300
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  • Radovi istraživača / Researchers’ publications
Institution
Pharmacy

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