A general derivative spectrophotometric method for determination of acidity constants is developed. The method appears suitable in cases when classical spectrophotometry cannot be employed due to little differences in the absorption spectra of conjugated acid-base pairs. Based on theoretical considerations, seven variants of the method have been established and their validity was checked, determining acidity constants of lorazepam and flurazepam as model compounds.
TY - JOUR
AU - Popović, Gordana
AU - Pfendt, Lidija
AU - Moskovljević, VM
PY - 2001
UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/300
AB - A general derivative spectrophotometric method for determination of acidity constants is developed. The method appears suitable in cases when classical spectrophotometry cannot be employed due to little differences in the absorption spectra of conjugated acid-base pairs. Based on theoretical considerations, seven variants of the method have been established and their validity was checked, determining acidity constants of lorazepam and flurazepam as model compounds.
PB - Elsevier Science BV, Amsterdam
T2 - Talanta
T1 - Derivative spectrophotometric method for determination of acidity constants of single step acid-base equilibria
VL - 55
IS - 2
SP - 363
EP - 370
DO - 10.1016/S0039-9140(01)00433-7
ER -
@article{
author = "Popović, Gordana and Pfendt, Lidija and Moskovljević, VM",
year = "2001",
abstract = "A general derivative spectrophotometric method for determination of acidity constants is developed. The method appears suitable in cases when classical spectrophotometry cannot be employed due to little differences in the absorption spectra of conjugated acid-base pairs. Based on theoretical considerations, seven variants of the method have been established and their validity was checked, determining acidity constants of lorazepam and flurazepam as model compounds.",
publisher = "Elsevier Science BV, Amsterdam",
journal = "Talanta",
title = "Derivative spectrophotometric method for determination of acidity constants of single step acid-base equilibria",
volume = "55",
number = "2",
pages = "363-370",
doi = "10.1016/S0039-9140(01)00433-7"
}
Popović, G., Pfendt, L.,& Moskovljević, V.. (2001). Derivative spectrophotometric method for determination of acidity constants of single step acid-base equilibria. in Talanta
Elsevier Science BV, Amsterdam., 55(2), 363-370.
https://doi.org/10.1016/S0039-9140(01)00433-7
Popović G, Pfendt L, Moskovljević V. Derivative spectrophotometric method for determination of acidity constants of single step acid-base equilibria. in Talanta. 2001;55(2):363-370.
doi:10.1016/S0039-9140(01)00433-7 .
Popović, Gordana, Pfendt, Lidija, Moskovljević, VM, "Derivative spectrophotometric method for determination of acidity constants of single step acid-base equilibria" in Talanta, 55, no. 2 (2001):363-370,
https://doi.org/10.1016/S0039-9140(01)00433-7 . .
