Influence of nine different solvents, either alone or in a mixture, on the retention behavior of ziprasidone and its five impurities were examined by normal-phase thin-layer chromatography. Migration distances of the examined compounds obtained under the examined chromatographic conditions were correlated with calculated mobile phase properties, such as Snyder polarity and Hansen solubility. Linear or second-order polynomial relationships with high correlation coefficients were established between investigated variables. The obtained mathematical functions and statistical results indicated that selected mobile phase properties can be used for the prediction of the retention behavior of ziprasidone and its five impurities. [GRAPHICS] .
Source:
Journal of Liquid Chromatography & Related Technologies, 2017, 40, 5-6, 247-251
TY - JOUR
AU - Obradović, Darija
AU - Oljačić, Slavica
AU - Nikolić, Katarina
AU - Agbaba, Danica
PY - 2017
UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3016
AB - Influence of nine different solvents, either alone or in a mixture, on the retention behavior of ziprasidone and its five impurities were examined by normal-phase thin-layer chromatography. Migration distances of the examined compounds obtained under the examined chromatographic conditions were correlated with calculated mobile phase properties, such as Snyder polarity and Hansen solubility. Linear or second-order polynomial relationships with high correlation coefficients were established between investigated variables. The obtained mathematical functions and statistical results indicated that selected mobile phase properties can be used for the prediction of the retention behavior of ziprasidone and its five impurities. [GRAPHICS] .
PB - Taylor & Francis Inc, Philadelphia
T2 - Journal of Liquid Chromatography & Related Technologies
T1 - Influence of selected mobile phase properties on the TLC retention behavior of ziprasidone and its impurities
VL - 40
IS - 5-6
SP - 247
EP - 251
DO - 10.1080/10826076.2017.1298026
ER -
@article{
author = "Obradović, Darija and Oljačić, Slavica and Nikolić, Katarina and Agbaba, Danica",
year = "2017",
abstract = "Influence of nine different solvents, either alone or in a mixture, on the retention behavior of ziprasidone and its five impurities were examined by normal-phase thin-layer chromatography. Migration distances of the examined compounds obtained under the examined chromatographic conditions were correlated with calculated mobile phase properties, such as Snyder polarity and Hansen solubility. Linear or second-order polynomial relationships with high correlation coefficients were established between investigated variables. The obtained mathematical functions and statistical results indicated that selected mobile phase properties can be used for the prediction of the retention behavior of ziprasidone and its five impurities. [GRAPHICS] .",
publisher = "Taylor & Francis Inc, Philadelphia",
journal = "Journal of Liquid Chromatography & Related Technologies",
title = "Influence of selected mobile phase properties on the TLC retention behavior of ziprasidone and its impurities",
volume = "40",
number = "5-6",
pages = "247-251",
doi = "10.1080/10826076.2017.1298026"
}
Obradović, D., Oljačić, S., Nikolić, K.,& Agbaba, D.. (2017). Influence of selected mobile phase properties on the TLC retention behavior of ziprasidone and its impurities. in Journal of Liquid Chromatography & Related Technologies
Taylor & Francis Inc, Philadelphia., 40(5-6), 247-251.
https://doi.org/10.1080/10826076.2017.1298026
Obradović D, Oljačić S, Nikolić K, Agbaba D. Influence of selected mobile phase properties on the TLC retention behavior of ziprasidone and its impurities. in Journal of Liquid Chromatography & Related Technologies. 2017;40(5-6):247-251.
doi:10.1080/10826076.2017.1298026 .
Obradović, Darija, Oljačić, Slavica, Nikolić, Katarina, Agbaba, Danica, "Influence of selected mobile phase properties on the TLC retention behavior of ziprasidone and its impurities" in Journal of Liquid Chromatography & Related Technologies, 40, no. 5-6 (2017):247-251,
https://doi.org/10.1080/10826076.2017.1298026 . .
