Show simple item record

dc.creatorKlisić, Aleksandra
dc.creatorKavarić, Nebojša
dc.creatorBjelaković, Bojko
dc.creatorSoldatović, Ivan
dc.creatorMartinović, Milica
dc.creatorKotur-Stevuljević, Jelena
dc.date.accessioned2019-09-02T12:02:44Z
dc.date.available2019-09-02T12:02:44Z
dc.date.issued2017
dc.identifier.issn0353-9466
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/3017
dc.description.abstractRetinol-binding protein 4 (RBP4) is an emerging risk factor for atherosclerotic disease in adults. However, to our knowledge, there are no studies examining the relationship between RBP4 and cardiovascular risk in young population. Therefore, we aimed to estimate this potential relationship in overweight/obese adolescent girls. Seventy overweight/obese adolescent girls, mean age 17.6 +/- 1.20 years, were included. Anthropometric and biochemical parameters were measured. Cardiovascular risk score (CVRS) was calculated by adding points for each risk factor (e.g., sex, high-density lipoprotein cholesterol (HDL-c), non-HDL-c, smoking, blood pressure and fasting glycemia). According to the risk status, we divided adolescent girls into low, medium and high risk groups (-2 lt = CVRS lt = 1, 2 lt = CVRS 54 and CVRS >= 5, respectively). We found significantly higher RBP4 in the high risk group as compared with low risk group (p lt 0.001). However, multiple linear regression analysis showed waist circumference (beta=0.257, p=0.031) to be the only independent predictor of higher cardiovascular risk (adjusted R'=0.342, p lt 0.001). In conclusion, RBP4 may be associated with higher cardiovascular risk in overweight/obese adolescent girls, but this association is mediated by abdominal obesity.en
dc.publisherSestre Milosrdnice Univ Hospital, Zagreb
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/175035/RS//
dc.rightsopenAccess
dc.sourceActa Clinica Croatica
dc.titleThe association between retinol-binding protein 4 and cardiovascular risk score is mediated by waist circumference in overweight/obese adolescent girlsen
dc.typearticle
dc.rights.licenseBY-NC-ND
dcterms.abstractСолдатовић, Иван; Каварић, Небојша; Бјелаковић, Бојко; Клисић, Aлександра; Котур-Стевуљевић, Јелена; Мартиновић, Милица;
dc.citation.volume56
dc.citation.issue1
dc.citation.spage92
dc.citation.epage98
dc.citation.other56(1): 92-98
dc.citation.rankM23
dc.identifier.wos000401782900014
dc.identifier.doi10.20471/acc.2017.56.01.14
dc.identifier.pmid29120147
dc.identifier.scopus2-s2.0-85024871721
dc.identifier.fulltexthttp://farfar.pharmacy.bg.ac.rs//bitstream/id/1625/3015.pdf
dc.identifier.rcubconv_3853
dc.type.versionpublishedVersion


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record