A review of published data on acridine derivatives with different biological activities
Abstract
Acridine ring can be found in molecules used in many different spheres, including industry and medicine. Nowadays, even acridines with antibacterial activity are of research interest due to increasing bacterial resistance. Some acridine derivatives showed antimalarial or antiviral activity. Acridine derivatives were also investigated for antitumor activity due to the interaction with topoisomerase II and DNA base pairs. Considering these possible uses of acridine derivatives, this work was made as overview of all significant structure characteristics for specific action of these compounds.
Keywords:
acridine / antiparasitic / antibacterial / antiviral / antitumor activity / DNASource:
Kragujevac Journal of Science, 2018, 40, 83-101Publisher:
- Univerzitet u Kragujevcu - Prirodno-matematički fakultet, Kragujevac
Funding / projects:
- Development of molecules with antiinflammatory and cardioprotective activity: structural modifications, modelling, physicochemical characterization and formulation investigations (RS-MESTD-Basic Research (BR or ON)-172041)
Collections
Institution/Community
PharmacyTY - JOUR AU - Rupar, Jelena AU - Dobričić, Vladimir AU - Aleksić, Mara AU - Brborić, Jasmina AU - Čudina, Olivera PY - 2018 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3033 AB - Acridine ring can be found in molecules used in many different spheres, including industry and medicine. Nowadays, even acridines with antibacterial activity are of research interest due to increasing bacterial resistance. Some acridine derivatives showed antimalarial or antiviral activity. Acridine derivatives were also investigated for antitumor activity due to the interaction with topoisomerase II and DNA base pairs. Considering these possible uses of acridine derivatives, this work was made as overview of all significant structure characteristics for specific action of these compounds. PB - Univerzitet u Kragujevcu - Prirodno-matematički fakultet, Kragujevac T2 - Kragujevac Journal of Science T1 - A review of published data on acridine derivatives with different biological activities IS - 40 SP - 83 EP - 101 DO - 10.5937/KgJSci1840083R ER -
@article{ author = "Rupar, Jelena and Dobričić, Vladimir and Aleksić, Mara and Brborić, Jasmina and Čudina, Olivera", year = "2018", abstract = "Acridine ring can be found in molecules used in many different spheres, including industry and medicine. Nowadays, even acridines with antibacterial activity are of research interest due to increasing bacterial resistance. Some acridine derivatives showed antimalarial or antiviral activity. Acridine derivatives were also investigated for antitumor activity due to the interaction with topoisomerase II and DNA base pairs. Considering these possible uses of acridine derivatives, this work was made as overview of all significant structure characteristics for specific action of these compounds.", publisher = "Univerzitet u Kragujevcu - Prirodno-matematički fakultet, Kragujevac", journal = "Kragujevac Journal of Science", title = "A review of published data on acridine derivatives with different biological activities", number = "40", pages = "83-101", doi = "10.5937/KgJSci1840083R" }
Rupar, J., Dobričić, V., Aleksić, M., Brborić, J.,& Čudina, O.. (2018). A review of published data on acridine derivatives with different biological activities. in Kragujevac Journal of Science Univerzitet u Kragujevcu - Prirodno-matematički fakultet, Kragujevac.(40), 83-101. https://doi.org/10.5937/KgJSci1840083R
Rupar J, Dobričić V, Aleksić M, Brborić J, Čudina O. A review of published data on acridine derivatives with different biological activities. in Kragujevac Journal of Science. 2018;(40):83-101. doi:10.5937/KgJSci1840083R .
Rupar, Jelena, Dobričić, Vladimir, Aleksić, Mara, Brborić, Jasmina, Čudina, Olivera, "A review of published data on acridine derivatives with different biological activities" in Kragujevac Journal of Science, no. 40 (2018):83-101, https://doi.org/10.5937/KgJSci1840083R . .