ФарФаР - Фармацеутски факултет, репозиторијум
Универзитет у Београду, Фармацеутски факултет
    • English
    • Српски
    • Српски (Serbia)
  • Српски (ћирилица) 
    • Енглески
    • Српски (ћирилица)
    • Српски (латиница)
  • Пријава
Преглед записа 
  •   ФарФаР
  • Pharmacy
  • Radovi istraživača / Researchers’ publications
  • Преглед записа
  •   ФарФаР
  • Pharmacy
  • Radovi istraživača / Researchers’ publications
  • Преглед записа
JavaScript is disabled for your browser. Some features of this site may not work without it.

Analytical Approaches to the Characterization of Solid Drug Delivery Systems with Porous Adsorbent Carriers

Само за регистроване кориснике
2018
Аутори
Krstić, Marko
Ražić, Slavica
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документу
Апстракт
A large variety of analytical techniques are available to meet the needs of characterization of solid samples. But, when solid drug delivery systems are concerned we are faced with demanding methodologies which have to compile capabilities of analytical techniques in regard to large diversity of structures and surface functionality of analyzed adsorbent carriers. In this review, the most commonly used analytical techniques are presented with their basic principles, advantages and disadvantages in applications of interest. Adsorbent carriers are widely used today as ingredients in the formulation of pharmaceutical forms, for increasing the dissolution rate of the drug and hence the bioavailability. They are also used in the formulation of substances with modified or target drug release into a specific tissue. Methods of thermal analysis (Thermogravimetry - TGA, Differential Scanning Calorimetry - DSC and Thermal microscopy - TM), spectroscopic methods (Infrared Spectroscopy - IR, especi...ally Fourier Transform Infrared Spectroscopy - FTIR and Raman spectroscopy), crystallographic methods (Powder X-Ray Diffraction - PXRD) and finally Scanning Electron Microscopy (SEM) are the most powerful in the characterization of modern therapeutic systems with porous adsorbents. The problem-solving power of each particular analytical method is often enhanced by using simultaneous methods rather than a single technique.

Кључне речи:
Thermal analysis / TA / Infrared Spectroscopy / IR / Fourier Transform Infrared Spectroscopy / FTIR / Raman spectroscopy / Powder X-Ray Diffraction / PXRD / Scanning Electron Microscopy (SEM) and drug dissolution
Извор:
Current Medicinal Chemistry, 2018, 25, 33, 3956-3972
Издавач:
  • Bentham Science Publ Ltd, Sharjah
Финансирање / пројекти:
  • Развој производа и технологија које обезбеђују жељено ослобађање лековитих супстанци из чврстих фармацеутских облика (RS-34007)

DOI: 10.2174/0929867325666180212120908

ISSN: 0929-8673

PubMed: 29436989

WoS: 000448120700002

Scopus: 2-s2.0-85055634182
[ Google Scholar ]
1
URI
https://farfar.pharmacy.bg.ac.rs/handle/123456789/3046
Колекције
  • Radovi istraživača / Researchers’ publications
Институција/група
Pharmacy
TY  - JOUR
AU  - Krstić, Marko
AU  - Ražić, Slavica
PY  - 2018
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3046
AB  - A large variety of analytical techniques are available to meet the needs of characterization of solid samples. But, when solid drug delivery systems are concerned we are faced with demanding methodologies which have to compile capabilities of analytical techniques in regard to large diversity of structures and surface functionality of analyzed adsorbent carriers. In this review, the most commonly used analytical techniques are presented with their basic principles, advantages and disadvantages in applications of interest. Adsorbent carriers are widely used today as ingredients in the formulation of pharmaceutical forms, for increasing the dissolution rate of the drug and hence the bioavailability. They are also used in the formulation of substances with modified or target drug release into a specific tissue. Methods of thermal analysis (Thermogravimetry - TGA, Differential Scanning Calorimetry - DSC and Thermal microscopy - TM), spectroscopic methods (Infrared Spectroscopy - IR, especially Fourier Transform Infrared Spectroscopy - FTIR and Raman spectroscopy), crystallographic methods (Powder X-Ray Diffraction - PXRD) and finally Scanning Electron Microscopy (SEM) are the most powerful in the characterization of modern therapeutic systems with porous adsorbents. The problem-solving power of each particular analytical method is often enhanced by using simultaneous methods rather than a single technique.
PB  - Bentham Science Publ Ltd, Sharjah
T2  - Current Medicinal Chemistry
T1  - Analytical Approaches to the Characterization of Solid Drug Delivery Systems with Porous Adsorbent Carriers
VL  - 25
IS  - 33
SP  - 3956
EP  - 3972
DO  - 10.2174/0929867325666180212120908
ER  - 
@article{
author = "Krstić, Marko and Ražić, Slavica",
year = "2018",
abstract = "A large variety of analytical techniques are available to meet the needs of characterization of solid samples. But, when solid drug delivery systems are concerned we are faced with demanding methodologies which have to compile capabilities of analytical techniques in regard to large diversity of structures and surface functionality of analyzed adsorbent carriers. In this review, the most commonly used analytical techniques are presented with their basic principles, advantages and disadvantages in applications of interest. Adsorbent carriers are widely used today as ingredients in the formulation of pharmaceutical forms, for increasing the dissolution rate of the drug and hence the bioavailability. They are also used in the formulation of substances with modified or target drug release into a specific tissue. Methods of thermal analysis (Thermogravimetry - TGA, Differential Scanning Calorimetry - DSC and Thermal microscopy - TM), spectroscopic methods (Infrared Spectroscopy - IR, especially Fourier Transform Infrared Spectroscopy - FTIR and Raman spectroscopy), crystallographic methods (Powder X-Ray Diffraction - PXRD) and finally Scanning Electron Microscopy (SEM) are the most powerful in the characterization of modern therapeutic systems with porous adsorbents. The problem-solving power of each particular analytical method is often enhanced by using simultaneous methods rather than a single technique.",
publisher = "Bentham Science Publ Ltd, Sharjah",
journal = "Current Medicinal Chemistry",
title = "Analytical Approaches to the Characterization of Solid Drug Delivery Systems with Porous Adsorbent Carriers",
volume = "25",
number = "33",
pages = "3956-3972",
doi = "10.2174/0929867325666180212120908"
}
Krstić, M.,& Ražić, S.. (2018). Analytical Approaches to the Characterization of Solid Drug Delivery Systems with Porous Adsorbent Carriers. in Current Medicinal Chemistry
Bentham Science Publ Ltd, Sharjah., 25(33), 3956-3972.
https://doi.org/10.2174/0929867325666180212120908
Krstić M, Ražić S. Analytical Approaches to the Characterization of Solid Drug Delivery Systems with Porous Adsorbent Carriers. in Current Medicinal Chemistry. 2018;25(33):3956-3972.
doi:10.2174/0929867325666180212120908 .
Krstić, Marko, Ražić, Slavica, "Analytical Approaches to the Characterization of Solid Drug Delivery Systems with Porous Adsorbent Carriers" in Current Medicinal Chemistry, 25, no. 33 (2018):3956-3972,
https://doi.org/10.2174/0929867325666180212120908 . .

DSpace software copyright © 2002-2015  DuraSpace
О ФарФаР-у | Пошаљите запажања

OpenAIRERCUB
 

 

Комплетан репозиторијумГрупеАуториНасловиТемеОва институцијаАуториНасловиТеме

Статистика

Преглед статистика

DSpace software copyright © 2002-2015  DuraSpace
О ФарФаР-у | Пошаљите запажања

OpenAIRERCUB