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dc.creatorKrstić, Marko
dc.creatorRažić, Slavica
dc.date.accessioned2019-09-02T12:03:26Z
dc.date.available2019-09-02T12:03:26Z
dc.date.issued2018
dc.identifier.issn0929-8673
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/3046
dc.description.abstractA large variety of analytical techniques are available to meet the needs of characterization of solid samples. But, when solid drug delivery systems are concerned we are faced with demanding methodologies which have to compile capabilities of analytical techniques in regard to large diversity of structures and surface functionality of analyzed adsorbent carriers. In this review, the most commonly used analytical techniques are presented with their basic principles, advantages and disadvantages in applications of interest. Adsorbent carriers are widely used today as ingredients in the formulation of pharmaceutical forms, for increasing the dissolution rate of the drug and hence the bioavailability. They are also used in the formulation of substances with modified or target drug release into a specific tissue. Methods of thermal analysis (Thermogravimetry - TGA, Differential Scanning Calorimetry - DSC and Thermal microscopy - TM), spectroscopic methods (Infrared Spectroscopy - IR, especially Fourier Transform Infrared Spectroscopy - FTIR and Raman spectroscopy), crystallographic methods (Powder X-Ray Diffraction - PXRD) and finally Scanning Electron Microscopy (SEM) are the most powerful in the characterization of modern therapeutic systems with porous adsorbents. The problem-solving power of each particular analytical method is often enhanced by using simultaneous methods rather than a single technique.en
dc.publisherBentham Science Publ Ltd, Sharjah
dc.relationinfo:eu-repo/grantAgreement/MESTD/Technological Development (TD or TR)/34007/RS//
dc.rightsrestrictedAccess
dc.sourceCurrent Medicinal Chemistry
dc.subjectThermal analysisen
dc.subjectTAen
dc.subjectInfrared Spectroscopyen
dc.subjectIRen
dc.subjectFourier Transform Infrared Spectroscopyen
dc.subjectFTIRen
dc.subjectRaman spectroscopyen
dc.subjectPowder X-Ray Diffractionen
dc.subjectPXRDen
dc.subjectScanning Electron Microscopy (SEM) and drug dissolutionen
dc.titleAnalytical Approaches to the Characterization of Solid Drug Delivery Systems with Porous Adsorbent Carriersen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractКрстић, Марко; Ражић, Славица;
dc.citation.volume25
dc.citation.issue33
dc.citation.spage3956
dc.citation.epage3972
dc.citation.other25(33): 3956-3972
dc.citation.rankM21
dc.identifier.wos000448120700002
dc.identifier.doi10.2174/0929867325666180212120908
dc.identifier.pmid29436989
dc.identifier.scopus2-s2.0-85055634182
dc.identifier.rcubconv_4238
dc.type.versionpublishedVersion


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