Aim of this study was to analyze how modifications in circulation chamber dimensions affect aerosol particle deposition in a Dry Powder Inhaler (DPI) Aerolizer. Combining computational fluid dynamics (CFD), for simulation of fluid flow (air), with discrete phase model (DPM) for particles simulation, we can better understand particle dispersion within inhaler's air flow field. Input in the simulation was 20mg of aerosol particles with initial velocity of 11,79166m/s. Dimension change influences maximum velocities, as well as percentage of deposited particles. Based on these information we were able to calculate the number of particles on the outlet and compare efficiency reduction when circulation chamber height increased. Knowledge obtained in this way can help in device performance optimization.
TY - CONF
AU - Sustersić, Tijana
AU - Vulović, Aleksandra
AU - Filipović, Nenad
AU - Cvijić, Sandra
AU - Ibrić, Svetlana
PY - 2018
UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3106
AB - Aim of this study was to analyze how modifications in circulation chamber dimensions affect aerosol particle deposition in a Dry Powder Inhaler (DPI) Aerolizer. Combining computational fluid dynamics (CFD), for simulation of fluid flow (air), with discrete phase model (DPM) for particles simulation, we can better understand particle dispersion within inhaler's air flow field. Input in the simulation was 20mg of aerosol particles with initial velocity of 11,79166m/s. Dimension change influences maximum velocities, as well as percentage of deposited particles. Based on these information we were able to calculate the number of particles on the outlet and compare efficiency reduction when circulation chamber height increased. Knowledge obtained in this way can help in device performance optimization.
PB - Institute of Electrical and Electronics Engineers Inc.
C3 - Proceedings - 2017 IEEE 17th International Conference on Bioinformatics and Bioengineering, BIBE 201
T1 - Effect of Circulation Chamber Dimensions on Aerosol Delivery Efficiency of a Commertial Dry Powder Inhaler Aerolizer (R)
SP - 555
EP - 558
DO - 10.1109/BIBE.2017.00011
ER -
@conference{
author = "Sustersić, Tijana and Vulović, Aleksandra and Filipović, Nenad and Cvijić, Sandra and Ibrić, Svetlana",
year = "2018",
abstract = "Aim of this study was to analyze how modifications in circulation chamber dimensions affect aerosol particle deposition in a Dry Powder Inhaler (DPI) Aerolizer. Combining computational fluid dynamics (CFD), for simulation of fluid flow (air), with discrete phase model (DPM) for particles simulation, we can better understand particle dispersion within inhaler's air flow field. Input in the simulation was 20mg of aerosol particles with initial velocity of 11,79166m/s. Dimension change influences maximum velocities, as well as percentage of deposited particles. Based on these information we were able to calculate the number of particles on the outlet and compare efficiency reduction when circulation chamber height increased. Knowledge obtained in this way can help in device performance optimization.",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
journal = "Proceedings - 2017 IEEE 17th International Conference on Bioinformatics and Bioengineering, BIBE 201",
title = "Effect of Circulation Chamber Dimensions on Aerosol Delivery Efficiency of a Commertial Dry Powder Inhaler Aerolizer (R)",
pages = "555-558",
doi = "10.1109/BIBE.2017.00011"
}
Sustersić, T., Vulović, A., Filipović, N., Cvijić, S.,& Ibrić, S.. (2018). Effect of Circulation Chamber Dimensions on Aerosol Delivery Efficiency of a Commertial Dry Powder Inhaler Aerolizer (R). in Proceedings - 2017 IEEE 17th International Conference on Bioinformatics and Bioengineering, BIBE 201
Institute of Electrical and Electronics Engineers Inc.., 555-558.
https://doi.org/10.1109/BIBE.2017.00011
Sustersić T, Vulović A, Filipović N, Cvijić S, Ibrić S. Effect of Circulation Chamber Dimensions on Aerosol Delivery Efficiency of a Commertial Dry Powder Inhaler Aerolizer (R). in Proceedings - 2017 IEEE 17th International Conference on Bioinformatics and Bioengineering, BIBE 201. 2018;:555-558.
doi:10.1109/BIBE.2017.00011 .
Sustersić, Tijana, Vulović, Aleksandra, Filipović, Nenad, Cvijić, Sandra, Ibrić, Svetlana, "Effect of Circulation Chamber Dimensions on Aerosol Delivery Efficiency of a Commertial Dry Powder Inhaler Aerolizer (R)" in Proceedings - 2017 IEEE 17th International Conference on Bioinformatics and Bioengineering, BIBE 201 (2018):555-558,
https://doi.org/10.1109/BIBE.2017.00011 . .
