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dc.creatorMilenković, Marina
dc.creatorStošović, Jelena
dc.creatorSlavkovska, Violeta
dc.date.accessioned2019-09-02T12:05:59Z
dc.date.available2019-09-02T12:05:59Z
dc.date.issued2018
dc.identifier.issn1934-578X
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/3146
dc.description.abstractThe subject of the study was the investigation of the chemical composition and antimicrobial activity of the essential oils (EOs) isolated from Calamintha sylvatica, C. vardarensis, C. nepeta and C. glandulosa, as well as their antibacterial activity in combination with antibiotics. The quantitative and qualitative analysis of EOs was performed using the GC/FID and GC/MS methods. The antimicrobial activity of EOs against six standard bacterial strains and one strain of yeast was tested using the broth microdilution method, while the antimicrobial activity of a combination of essential oils and gentamicin/ciprofloxacin was tested by the checkerboard method. The dominant components (> 10%) of the essential oils were: cis-piperitone epoxide and menthone (C. sylvatica), pulegone and menthone (C. vardarensis), pulegone and piperitenone (C. nepeta), pulegone, piperitenone, menthone and piperitone (C. glandulosa). EOs did not exhibit significant antimicrobial activity except the essential oil of C. vardarensis which was selectively active against Staphylococcus aureus (MIC - 21.25 mu g/mL). The overall effect of essential oil-antibiotic combinations varied from synergistic (FICI lt = 0.5) to antagonistic (FICI >= 2) depending on the bacterial strain tested.en
dc.publisherSage Publications Inc, Thousand Oaks
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173021/RS//
dc.rightsopenAccess
dc.sourceNatural Product Communications
dc.subjectCalamintha speciesen
dc.subjectEssential oilen
dc.subjectAntimicrobial activityen
dc.subjectSynergistic effecten
dc.titleSynergy between Essential Oils of Calamintha Species (Lamiaceae) and Antibioticsen
dc.typearticle
dc.rights.licenseBY-NC
dcterms.abstractСтосовић, Јелена; Миленковић, Марина; Славковска, Виолета;
dc.citation.volume13
dc.citation.issue3
dc.citation.spage371
dc.citation.epage374
dc.citation.other13(3): 371-374
dc.citation.rankM23
dc.identifier.wos000433651800027
dc.identifier.scopus2-s2.0-85048165424
dc.identifier.fulltexthttp://farfar.pharmacy.bg.ac.rs/bitstream/id/7342/bitstream_7342.pdf
dc.identifier.rcubconv_4127
dc.type.versionpublishedVersion


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