Show simple item record

dc.creatorJugović, M
dc.creatorSpasojević-Kalimanovska, Vesna
dc.creatorSpasić, S
dc.creatorNikolić, Z
dc.date.accessioned2019-09-02T10:53:56Z
dc.date.available2019-09-02T10:53:56Z
dc.date.issued2002
dc.identifier.issn0354-3447
dc.identifier.urihttps://farfar.pharmacy.bg.ac.rs/handle/123456789/316
dc.description.abstractPatients with chronic renal insufficiency on hemodialysis develop lipoprotein abnormalities that may contribute to increased risk for atherosclerosis. The atherogenic risk for chronic renal insufficiency patients and dialysis treated patients was assessed by measuring total cholesterol, triglycerides, HDL-cholesterol, LDL-cholesterol and calculating the ratio: TC/HDL-C and LDL-C/HDL-C. The examined group consisted of 18 cronic renal insufficiency patients and 60 patients on hemodialysis. The results were compared to a control group of 85 voluntary blood donors. Serum lipid parameters were examined by standard methods. All lipid parameters in hemodialysis patients were statistically different compared to the control group (p lt 0.05) while chronic renal insufficiency patients showed significant difference only in triglycerides and HDL-cholesterol. Hypertriglyceridemia was present in both examined groups of patients and HDL-cholesterol was lower within both groups. All calculated atherogenic ratios were higher for patients than the control group. Lipid parameters were compared between chronic renal insufficiency and hemodialysis patients but statistical significantly difference was obtained only for HDL-cholesterol (p lt 0.05). We conclude that increased values of triglycerides and lower HDL-cholesterol in chronic renal insufficiency patients contribute to high incidence of cardiovascular disease. Chronic renal insufficiency patients have impaired reverse cholesterol transport from peripheral cells to lipoproteins, decreased levels of HDL-cholesterol, hypertriglyceridemia prevalence of small, dense LDL and increased levels of potentially atherogenic remnant particles.en
dc.publisherDruštvo medicinskih biohemičara Srbije i Crne Gore, Beograd i Univerzitet u Beogradu - Farmaceutski fakultet, Beograd
dc.rightsrestrictedAccess
dc.sourceJugoslovenska medicinska biohemija
dc.titleLipoprotein metabolism abnormalities in patients with chronic renal insufficiencyen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractНиколић, З; Спасојевић-Калимановска, Весна; Спасић, С; Југовић, М;
dc.citation.volume21
dc.citation.issue4
dc.citation.spage323
dc.citation.epage330
dc.citation.other21(4): 323-330
dc.citation.rankM23
dc.identifier.wos000180396900003
dc.identifier.doi10.2298/JMH0204323J
dc.identifier.scopus2-s2.0-0036821687
dc.identifier.rcubconv_1381
dc.type.versionpublishedVersion


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record