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dc.creatorKavarić, Nebojša
dc.creatorKlisić, Aleksandra
dc.creatorNinić, Ana
dc.date.accessioned2019-09-02T12:06:50Z
dc.date.available2019-09-02T12:06:50Z
dc.date.issued2018
dc.identifier.issn0887-8013
dc.identifier.urihttps://farfar.pharmacy.bg.ac.rs/handle/123456789/3175
dc.description.abstractBackgroundVisceral adiposity index (VAI) and Lipid accumulation product (LAP) are novel visceral adiposity indexes, proposed for the evaluation of cardiometabolic risk in adult population. Considering contradictory results obtained from many studies so far, we aimed to examine the potential benefit of applicability of VAI and LAP, over simple anthropometric indices and traditional lipid parameters in individuals with type 2 diabetes mellitus (DM2). MethodsA total of 180 DM2 (of them 50% females) and 119 controls who volunteered to participate in this cross-sectional study were enrolled. Anthropometric and biochemical parameters, as well as blood pressure were obtained. VAI and LAP were calculated. ResultsMultivariate logistic regression analysis showed that high-density lipoprotein cholesterol (HDL-c), (P lt .001), waist circumference (WC), (P=.027), age (P=.001), hypolipemic therapy (P=.024), and LAP (P=.005) were independent predictors of DM2 in adjusted models. In Receiver Operating Characteristic curve analysis, used to discriminate subjects with DM2 from those who did not have it, good accuracy of the applied procedures was only achieved with models which were consisted of parameters used in VAI (Body mass index, WC, HDL-c, triglycerides) and LAP (WC, triglycerides) indexes equations, respectively [Area under the curve (AUC)=0.819 and AUC=0.800, respectively], but not with VAI (AUC=0.781) and LAP (AUC=0.784) indexes themselves. ConclusionVisceral adiposity index and Lipid accumulation product may not be better than parameters that enter its equation in type 2 diabetes prediction.en
dc.publisherWiley, Hoboken
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/175035/RS//
dc.rightsrestrictedAccess
dc.sourceJournal of Clinical Laboratory Analysis
dc.subjectlipid accumulation producten
dc.subjectobesityen
dc.subjecttype 2 diabetes mellitusen
dc.subjectvisceral adiposity indexen
dc.titleAre visceral adiposity index and lipid accumulation product reliable indices for metabolic disturbances in patients with type 2 diabetes mellitus?en
dc.typearticle
dc.rights.licenseARR
dcterms.abstractКаварић, Небојша; Нинић, Aна; Клисић, Aлександра;
dc.citation.volume32
dc.citation.issue3
dc.citation.other32(3): -
dc.citation.rankM23
dc.identifier.wos000427567700008
dc.identifier.doi10.1002/jcla.22283
dc.identifier.pmid28632304
dc.identifier.scopus2-s2.0-85021276172
dc.type.versionpublishedVersion


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Приказ основних података о документу