A rapid and simple method has been developed for chromatographic separation of the pharmacologically active components of some antibypertensive drugs. The active compounds - lisinopril, cilazapril, captopril, quinapril, and ramipril - were successfully separated on aminoplast layers with benzene-cyclohexane-methyl ethyl ketone, 15 + 10 + 15 (v/v), as mobile phase. The mechanism of retention and the correlation between lipophilicity and log P were both investigated.
TY - JOUR
AU - Perišić-Janjić, Nada U.
AU - Agbaba, Danica
PY - 2002
UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/318
AB - A rapid and simple method has been developed for chromatographic separation of the pharmacologically active components of some antibypertensive drugs. The active compounds - lisinopril, cilazapril, captopril, quinapril, and ramipril - were successfully separated on aminoplast layers with benzene-cyclohexane-methyl ethyl ketone, 15 + 10 + 15 (v/v), as mobile phase. The mechanism of retention and the correlation between lipophilicity and log P were both investigated.
PB - Springer Nature
T2 - Journal of Planar Chromatography - Modern TLC
T1 - The retention behavior of antihypertensive drugs of the type angiotensin-converting enzyme inhibitors on thin layers of aminoplast
VL - 15
IS - 3
SP - 210
EP - 213
DO - 10.1556/JPC.15.2002.3.10
ER -
@article{
author = "Perišić-Janjić, Nada U. and Agbaba, Danica",
year = "2002",
abstract = "A rapid and simple method has been developed for chromatographic separation of the pharmacologically active components of some antibypertensive drugs. The active compounds - lisinopril, cilazapril, captopril, quinapril, and ramipril - were successfully separated on aminoplast layers with benzene-cyclohexane-methyl ethyl ketone, 15 + 10 + 15 (v/v), as mobile phase. The mechanism of retention and the correlation between lipophilicity and log P were both investigated.",
publisher = "Springer Nature",
journal = "Journal of Planar Chromatography - Modern TLC",
title = "The retention behavior of antihypertensive drugs of the type angiotensin-converting enzyme inhibitors on thin layers of aminoplast",
volume = "15",
number = "3",
pages = "210-213",
doi = "10.1556/JPC.15.2002.3.10"
}
Perišić-Janjić, N. U.,& Agbaba, D.. (2002). The retention behavior of antihypertensive drugs of the type angiotensin-converting enzyme inhibitors on thin layers of aminoplast. in Journal of Planar Chromatography - Modern TLC
Springer Nature., 15(3), 210-213.
https://doi.org/10.1556/JPC.15.2002.3.10
Perišić-Janjić NU, Agbaba D. The retention behavior of antihypertensive drugs of the type angiotensin-converting enzyme inhibitors on thin layers of aminoplast. in Journal of Planar Chromatography - Modern TLC. 2002;15(3):210-213.
doi:10.1556/JPC.15.2002.3.10 .
Perišić-Janjić, Nada U., Agbaba, Danica, "The retention behavior of antihypertensive drugs of the type angiotensin-converting enzyme inhibitors on thin layers of aminoplast" in Journal of Planar Chromatography - Modern TLC, 15, no. 3 (2002):210-213,
https://doi.org/10.1556/JPC.15.2002.3.10 . .
