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dc.creatorGrujić, Branka
dc.creatorVuković, Zdenka
dc.creatorVeljković-Giga, Jelena
dc.creatorIbrić, Svetlana
dc.creatorDekanski, Dragana
dc.date.accessioned2019-09-02T12:07:50Z
dc.date.available2019-09-02T12:07:50Z
dc.date.issued2018
dc.identifier.issn0367-598X
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/3217
dc.description.abstractNutrition and dietary supplements have a significant role in the prevention and treatment of cardiovascular disease. Olive and vine leaves, thanks to their constituents, represent powerful natural antioxidants exhibiting cardioprotective activity. High concentrations of active ingredients can be provided by means of extraction. Dry herbal extracts are highly sensitive to moisture and elevated temperature and from the pharmaceutical and technological point of view these are raw materials with inadequate technological properties. The aim of this study was to investigate and to compare the influence of different excipients in capsule formulation of these two dry extracts i.e. the selection of excipients that will ensure appropriate critical process parameters in the manufacturing procedure. The monitored quality characteristics include flowability, bulk density and tapped density that are critical for technological feasibility of the capsule-filling operation. The effects of excipients on the above parameters have been experimentally studied and the appropriate capsule formulations have been developed based on the obtained results, which will ensure homogeneity and stability of the preparation.en
dc.publisherSavez hemijskih inženjera, Beograd
dc.relationinfo:eu-repo/grantAgreement/MESTD/Technological Development (TD or TR)/34007/RS//
dc.rightsopenAccess
dc.sourceHemijska industrija
dc.subjectdry herbal extractsen
dc.subjectolive leafen
dc.subjectvine leafen
dc.subjectcapsulesen
dc.titleAn investigation into the effects of excipients on quality characteristics of a dry herbal extract containing capsuleen
dc.typearticle
dc.rights.licenseBY-NC-ND
dcterms.abstractГрујић, Бранка; Декански, Драгана; Ибрић, Светлана; Вуковић, Зденка; Вељковић-Гига, Јелена;
dc.citation.volume72
dc.citation.issue4
dc.citation.spage183
dc.citation.epage189
dc.citation.other72(4): 183-189
dc.citation.rankM23
dc.identifier.wos000440182100002
dc.identifier.doi10.2298/HEMIND180228012G
dc.identifier.scopus2-s2.0-85054031780
dc.identifier.fulltexthttp://farfar.pharmacy.bg.ac.rs//bitstream/id/1797/3215.pdf
dc.identifier.rcubconv_4182
dc.type.versionpublishedVersion


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