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dc.creatorArsenijević, Jelena
dc.creatorDrobac, Milica
dc.creatorŠoštarić, Ivan
dc.creatorJevdović, Radosav
dc.creatorŽivković, Jelena
dc.creatorRažić, Slavica
dc.creatorMoravcević, Đorđe
dc.creatorMaksimović, Zoran
dc.date.accessioned2019-09-02T12:10:27Z
dc.date.available2019-09-02T12:10:27Z
dc.date.issued2019
dc.identifier.issn0926-6690
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/3318
dc.description.abstractIn the present research, the chemical composition of aerial parts of cultivated citral chemotype of Thymus pannonicus All. (Lamiaceae), growing at different soil conditions was studied. Two plant lineages were unfertilized or treated using either nitrogen or phosphorus fertilizers at different concentration levels. Essential oil (EO) content, EO composition, and composition of hydromethanol extracts (MEs) were compared to the results obtained for wild growing plants in order to evaluate the potential of T. pannonicus for its industrial production. EO content (%, V/m) in cultivated samples varied between 0.32-0.75% and 0.62-1.05% within two examined lineages, whereas the herbs from the natural habitat contained 0.49-1.29% of EO. GC-FID/MS analysis showed that citral, i.e. mixture of isomers geranial and neral, was the most abundant constituent in all EOs (51.90-81.96%). HPLC analysis revealed that total caffeic acid derivatives, with rosmarinic acid (RA) as the most abundant compound in all extracts, as well as total apigenin glycosides contents were significantly higher in the extracts originating from the cultivated herbs (112.15-184.94 mg/g and 5.08-15.29 mg/g, respectively), in comparison to the extracts of the herbs from the natural habitats (67.61-98.75 mg/g and 1.17-1.32 mg/g). In general, the composition of cultivated herbs varied less than that of samples originating from natural habitats, indicating that controlled cultivation of citral chemotype of T. pannonicus can provide herbal drug with favourable characteristics. Only minor differences were observed between cultivated samples treated with different fertilizers.en
dc.publisherElsevier Science BV, Amsterdam
dc.relationinfo:eu-repo/grantAgreement/MESTD/Technological Development (TD or TR)/31089/RS//
dc.rightsrestrictedAccess
dc.sourceIndustrial Crops and Products
dc.subjectThymeen
dc.subjectCultivationen
dc.subjectFertilizeren
dc.subjectCitralen
dc.subjectRosmarinic aciden
dc.subjectApigenin glycosidesen
dc.titleComparison of essential oils and hydromethanol extracts of cultivated and wild growing Thymus pannonicus All.en
dc.typearticle
dc.rights.licenseARR
dcterms.abstractШоштарић, Иван; Дробац, Милица; Ражић, Славица; Живковић, Јелена; Јевдовић, Радосав; Моравцевић, Ђорђе; Максимовић, Зоран; Aрсенијевић, Јелена;
dc.citation.volume130
dc.citation.spage162
dc.citation.epage169
dc.citation.other130: 162-169
dc.citation.rankaM21
dc.identifier.wos000458942600020
dc.identifier.doi10.1016/j.indcrop.2018.12.055
dc.identifier.scopus2-s2.0-85059063027
dc.identifier.rcubconv_4164
dc.type.versionpublishedVersion


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