Modeling and optimization of bioactive compounds from chickpea seeds (Cicer arietinum L)
Само за регистроване кориснике
2019
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
The aim of study was to model and optimize the extraction of polyphenols and flavonoids with expressed antioxidant activity from chickpea seeds using a central composite design. The optimal extraction conditions were the extraction time of 145.5 min, ethanol concentration of 83.7% and liquid-to-solid ratio of 24.9 (expressed as cm(3) per g). The content of total polyphenol and flavonoid was 2.75 g gallic acid equivalent per kilogram of the dried extract and 0.147 g rutin equivalent per kilogram of the dried extract, respectively. Using 2,2-diphenyl-1-picrylhydrazyl assay, it was found that the optimal extract had the IC50 of 1.55 mg cm(-3).
Кључне речи:
Chickpea / total polyphenol / total flavonoid / antioxidant activity / central composite designИзвор:
Solid State Ionics, 2019, 54, 5, 837-846Издавач:
- Taylor & Francis Inc, Philadelphia
Финансирање / пројекти:
- Биљни и синтетички биоактивни производи новије генерације (RS-MESTD-Technological Development (TD or TR)-34012)
DOI: 10.1080/01496395.2018.1520720
ISSN: 0149-6395
WoS: 000464574300018
Scopus: 2-s2.0-85053510649
Институција/група
PharmacyTY - JOUR AU - Savić, Ivan AU - Nikolić, Ivana Lj. AU - Savić-Gajić, Ivana AU - Kundaković, Tatjana PY - 2019 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3362 AB - The aim of study was to model and optimize the extraction of polyphenols and flavonoids with expressed antioxidant activity from chickpea seeds using a central composite design. The optimal extraction conditions were the extraction time of 145.5 min, ethanol concentration of 83.7% and liquid-to-solid ratio of 24.9 (expressed as cm(3) per g). The content of total polyphenol and flavonoid was 2.75 g gallic acid equivalent per kilogram of the dried extract and 0.147 g rutin equivalent per kilogram of the dried extract, respectively. Using 2,2-diphenyl-1-picrylhydrazyl assay, it was found that the optimal extract had the IC50 of 1.55 mg cm(-3). PB - Taylor & Francis Inc, Philadelphia T2 - Solid State Ionics T1 - Modeling and optimization of bioactive compounds from chickpea seeds (Cicer arietinum L) VL - 54 IS - 5 SP - 837 EP - 846 DO - 10.1080/01496395.2018.1520720 ER -
@article{ author = "Savić, Ivan and Nikolić, Ivana Lj. and Savić-Gajić, Ivana and Kundaković, Tatjana", year = "2019", abstract = "The aim of study was to model and optimize the extraction of polyphenols and flavonoids with expressed antioxidant activity from chickpea seeds using a central composite design. The optimal extraction conditions were the extraction time of 145.5 min, ethanol concentration of 83.7% and liquid-to-solid ratio of 24.9 (expressed as cm(3) per g). The content of total polyphenol and flavonoid was 2.75 g gallic acid equivalent per kilogram of the dried extract and 0.147 g rutin equivalent per kilogram of the dried extract, respectively. Using 2,2-diphenyl-1-picrylhydrazyl assay, it was found that the optimal extract had the IC50 of 1.55 mg cm(-3).", publisher = "Taylor & Francis Inc, Philadelphia", journal = "Solid State Ionics", title = "Modeling and optimization of bioactive compounds from chickpea seeds (Cicer arietinum L)", volume = "54", number = "5", pages = "837-846", doi = "10.1080/01496395.2018.1520720" }
Savić, I., Nikolić, I. Lj., Savić-Gajić, I.,& Kundaković, T.. (2019). Modeling and optimization of bioactive compounds from chickpea seeds (Cicer arietinum L). in Solid State Ionics Taylor & Francis Inc, Philadelphia., 54(5), 837-846. https://doi.org/10.1080/01496395.2018.1520720
Savić I, Nikolić IL, Savić-Gajić I, Kundaković T. Modeling and optimization of bioactive compounds from chickpea seeds (Cicer arietinum L). in Solid State Ionics. 2019;54(5):837-846. doi:10.1080/01496395.2018.1520720 .
Savić, Ivan, Nikolić, Ivana Lj., Savić-Gajić, Ivana, Kundaković, Tatjana, "Modeling and optimization of bioactive compounds from chickpea seeds (Cicer arietinum L)" in Solid State Ionics, 54, no. 5 (2019):837-846, https://doi.org/10.1080/01496395.2018.1520720 . .